It is possible that the main title of the report Leukodystrophy is not the name you expected.
- Refsum Disease
- Cerebrotendinous Xanthomatosis
- Metachromatic Leukodystrophy
- Zellweger Syndrome Spectrum Disorders
- Krabbe Disease
- X-linked Adrenoleukodystrophy
- Multiple Sulfatase Deficiency
- Megalencephaly with Subcortical Cysts
- Pelizaeus-Merzbacher Disease
- Alexander Disease
- Canavan Disease
- Childhood Ataxia and Cerebral Hypomyelination (CACH)
- Other Leukodystrophies
Leukodystrophies are a group of very rare, progressive, metabolic, genetic diseases that affect the brain, spinal cord and often the peripheral nerves. Each type of leukodystrophy is caused by a specific gene abnormality that leads to abnormal development of one of at least 10 different chemicals that make up the white matter (myelin sheath) of the brain. The myelin sheath is the protective covering of the nerve and nerves can't function normally without it. Each type of leukodystrophy affects a different part of the myelin sheath, leading to a range of neurological problems.
Kennedy Krieger Institute
707 North Broadway
Baltimore, MD 21205
National Tay-Sachs and Allied Diseases Association, Inc.
2001 Beacon Street
Brookline, MA 02146-4227
United Leukodystrophy Foundation
224 N. 2nd St.
DeKalb, IL 60115
NIH/National Institute of Neurological Disorders and Stroke
P.O. Box 5801
Bethesda, MD 20824
Hunter's Hope Foundation, Inc.
PO Box 643
6368 West Quaker Street
Orchard Park, NY 14127
Australian Leukodystrophy Support Group, Inc.
54 Railway Road
Blackburn, VIC 3130
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Myelin Disorders Bioregistry Project (MDBP)
Childrens National Medical Center, c/o Dr. Adeline Vanderver
111 Michigan Ave., NW
Washington, DC 20010
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Last Updated: 4/28/2008
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