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“This moves the field forward in an impressive way, but like many breakthroughs, many questions remain to be answered,” he says.
There is only one drug approved for the treatment of ALS. It is used to slow disease progression but is not a cure. ALS Association President and CEO Jane H. Gilbert says effective therapies for ALS are long overdue.
“This is very exciting research that has huge promise for the discovery of new treatments,” she tells WebMD.
Lucie Bruijn, PhD, scientific director of the ALS Association, says she is optimistic that better drugs or drug combinations will emerge to slow disease progression.
Siddique is also optimistic that his team’s discovery could lead to better treatments for ALS and other diseases of the nerves.
“This is the most hopeful I have been in 25 years of research,” he says. “Previously, we were running in many different directions, but this is where we will focus from now on.”