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    Pemphigus

    Important
    It is possible that the main title of the report Pemphigus is not the name you expected.

    Disorder Subdivisions

    • drug-induced pemphigus
    • endemic pemphigus (fogo selvagem)
    • pemphigus erythematosus (Senear-Usher syndrome)
    • pemphigus foliaceus
    • pemphigus vegetans
    • pemphigus vulgaris

    General Discussion

    Pemphigus is a general term for a group of rare autoimmune blistering skin disorders. Autoimmune disorders occur when the body's own immune system mistakenly attacks healthy tissue. The symptoms and severity associated with the various forms of pemphigus vary. All forms of pemphigus are characterized by the development of blistering eruptions on the outer layer of the skin (epidermis). In pemphigus vulgaris, lesions also develop on the mucous membranes such as those lining the inside the mouth. Mucous membranes are the thin, moist coverings of many of the body's internal surfaces. If left untreated, pemphigus will usually be fatal. The exact cause of pemphigus is unknown.

    The term pemphigus is a general term for a group of related autoimmune blistering skin diseases. The two main types of pemphigus are pemphigus vulgaris and pemphigus foliaceus. Each type has subtypes. Additional disorders are sometimes classified as pemphigus including paraneoplastic pemphigus and pemphigus IgA. Some physicians consider these disorders similar, yet distinct, autoimmune blistering disorders with different causes and clinical, immunological and microscopic tissue (histological) features. Pemphigoid is a general term for a different group of skin disorders. These other disorders are discussed in the related disorders section of this report.

    Resources

    American Autoimmune Related Diseases Association, Inc.
    22100 Gratiot Ave.
    Eastpointe, MI 48021
    Tel: (586)776-3900
    Fax: (586)776-3903
    Tel: (800)598-4668
    Email: aarda@aarda.org
    Internet: http://www.aarda.org/

    NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases
    Information Clearinghouse
    One AMS Circle
    Bethesda, MD 20892-3675
    USA
    Tel: (301)495-4484
    Fax: (301)718-6366
    Tel: (877)226-4267
    TDD: (301)565-2966
    Email: NIAMSinfo@mail.nih.gov
    Internet: http://www.niams.nih.gov/

    International Pemphigus & Pemphigoid Foundation
    2701 Cottage Way
    Suite 16
    Sacramento, CA 95825
    USA
    Tel: (916)922-1298
    Fax: (916)922-1458
    Email: pemphigus@pemphigus.org
    Internet: http://www.pemphigus.org

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    Autoimmune Information Network, Inc.
    PO Box 4121
    Brick, NJ 08723
    Fax: (732)543-7285
    Email: autoimmunehelp@aol.com

    AutoImmunity Community
    Email: moderator@autoimmunitycommunity.org
    Internet: http://www.autoimmunitycommunity.org

    Australasian Blistering Diseases Foundation
    St. George Hospital,
    Department of Dermatology
    Gray Street
    Kogarah
    Sydney, NSW 2217
    Australia
    Tel: 0291132088
    Fax: 0291132886
    Email: info@blisters.org.au
    Internet: http://www.blisters.org.au/BDHome.html

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 11/15/2012
    Copyright 1985, 1987, 1988, 1989, 1990, 1992, 1996, 1999, 2000, 2002, 2003, 2006, 2007, 2009, 2012 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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