Dementia: Medicines to Treat Behavior Changes - Topic Overview
Anticonvulsant medicine, such as valproic acid, may be used to control agitation, violent behavior, and mood swings caused by dementia. But the U.S. Food and Drug Administration (FDA) has not approved this medicine for this specific problem.
The U.S. Food and Drug Administration (FDA) has issued a warning on anticonvulsants and the risk of suicide and suicidal thoughts. The FDA does not recommend that people stop using these medicines. Instead, people who take anticonvulsant medicine should be watched closely for warning signs of suicide. People who take anticonvulsant medicine and who are worried about this side effect should talk to a doctor.
Other medicines that may be used to treat agitation include antidepressants. Trazodone and serotonin reuptake inhibitors (SSRIs) such as citalopram, fluoxetine, and sertraline are examples. But research on the effectiveness of these medicines in Alzheimer's disease and other dementias is limited.
The U.S. Food and Drug Administration (FDA) has issued an advisory on antidepressant medicines and the risk of suicide. Talk to your doctor about these possible side effects and the warning signs of suicide.
See Drug Reference for more information about all of these medicines. (Drug Reference is not available in all systems.)