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    Central Pain Syndrome

    Important
    It is possible that the main title of the report Central Pain Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    • CPS

    Disorder Subdivisions

    General Discussion

    Summary
    Central pain syndrome is a neurological disorder caused by damage to the central nervous system (CNS). Common symptoms include pain and loss of sensation, usually in the face, arms and/or legs. Pain is often constant and can be mild, moderate, or severe in intensity. Affected individuals may become hypersensitive to painful stimuli. The specific type of pain experience can vary from one individual to another based, in part, upon the underlying cause of the disorder and the area of the central nervous system affected. Central pain syndrome can potentially disrupt an individual's daily routine. In severe cases, the pain can be agonizing and unrelenting and dramatically affect a person's quality of life. Central pain syndrome can develop following a variety of conditions including stroke, multiple sclerosis, spinal cord injury, or brain tumors.

    Introduction
    For years, it was believed that the majority of cases of central pain syndrome were due to damage of the thalamus most often caused by a stroke. The disorder was frequently referred to as thalamic pain syndrome or Dejerine-Roussy syndrome after two French neurologists who reported on the disorder in the early 1900s. In fact, to some degree central pain became synonymous with thalamic pain syndrome for many years. However, researchers now know that damage to other areas of the CNS can cause central pain syndrome, including cases following a stroke. Consequently, the preferred name for this group of disorders is central pain syndrome to acknowledge that damage to various areas of the CNS (and not predominantly the thalamus) can cause central pain and that a stroke is not necessarily the primary cause. The preferred term for the specific subtype of central pain syndrome caused by CNS damage due to a stroke is central post-stroke pain.

    Resources

    American Chronic Pain Association
    P.O. Box 850
    Rocklin, CA 95677
    USA
    Tel: (916)632-0922
    Fax: (916)652-8190
    Tel: (800)533-3231
    Email: ACPA@theacpa.org
    Internet: http://www.theacpa.org

    NIH/National Institute of Neurological Disorders and Stroke
    P.O. Box 5801
    Bethesda, MD 20824
    Tel: (301)496-5751
    Fax: (301)402-2186
    Tel: (800)352-9424
    TDD: (301)468-5981
    Internet: http://www.ninds.nih.gov/

    American Pain Society
    4700 West Lake Avenue
    Glenview, IL 60025
    Tel: (847)375-4715
    Fax: (866)574-2654
    Email: info@ampainsoc.org
    Internet: http://www.ampainsoc.org

    Pain.com
    c/o Dannemiller, Inc.
    5711 Northwest Parkway
    San Antonio, TX 78246
    Tel: (210)641-8311
    Fax: (210)641-8329
    Email: editor@pain.com
    Internet: http://www.pain.com

    International Association for the Study of Pain
    IASP Secretariat
    1510 H Street NW
    Suite 600
    Washington, DC 20005-1020
    Tel: (202)524-5300
    Fax: (202)524-5301
    Email: IASPdesk@iasp-pain.org
    Internet: http://www.iasp-pain.org

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    Irish Chronic Pain Association
    Coleraine House, Coleraine St.
    Dublin, 7
    Ireland
    Tel: 35318047567
    Fax: 35318047567
    Email: info@chronicpain.ie
    Internet: http://www.chronicpain.ie

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 6/21/2012
    Copyright 1990, 2003, 2012 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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