Metastatic Breast Cancer as a Chronic Condition
For women whose breast cancer has spread, treatments can improve their condition and add years to their life.
Treatments for Breast Cancer that Has Spread continued...
Newer treatment approaches have also done wonders to reduce the often
painful symptoms of the disease. "Supportive care has gotten a lot better,
so that the symptoms that people have from treatments and progression of the
disease are much more controlled," says Musa Mayer, survivor of stage II
breast cancer, patient advocate with the National Cancer Institute, and author
of Advanced Breast Cancer: A Guide to Living with Metastatic
For example, a class of drugs known as bisphosphonates -- both pill
medications like Fosamax and Actonel, and stronger versions given by
intravenous injection called Aredia and Zometa -- has changed things
dramatically for women with cancer that has spread to their bones.
"These drugs have been very beneficial, because they slow the breakdown
of bone. One of the big problems with bone metastases used to be
fractures," says Mayer. "With these drugs, you don't have the kind of
damaging, progressive bone disease that we used to see."
Living Well in Spite of the Unknown
But despite all the progress, a diagnosis of metastatic breast cancer is
still a fearful, life-changing one. "A lot of people are very afraid
initially, and feel that many doors have been closed to them," says Mary
Jane Massie, MD, attending psychiatrist at Sloan-Kettering's Breast Center.
"Our task is to help people see that they can move ahead with their
lives -- always needing excellent health care follow-up, but often living for
relatively uninterrupted periods of life."
The hardest part, for most women, is the uncertainty. "Over time, some
people get used to the idea that they'll be living with, or despite, the
disease, but they won't be rid of it. But what's hardest is confronting the
uncertainty and the general lack of control -- not just the disease and the
drugs, but more globally, the fact that we don't know what the next months will
bring with anyone with this disease," says Hudis.
Coping with the "extended marathon" of life with metastatic breast
cancer means different things to different women. Some seek support from
counselors or group therapy sessions at their cancer centers, while others find
it online. The web-based support group BCmets (www.bcmets.org) is one of the
oldest and largest.
"Some women want to keep working full time for as long as possible and
keep their focus away from the illness," says Mayer. "Others say, 'OK,
I have a limited time, and I don't want to spend it in my office. I want to
travel, work in my garden, spend time with my grandchildren.' Everyone has
One of the most important things for women with breast cancer metastases to
remember, says Winer, is the exciting progress of research. "This doesn't
mean that we'll have new treatments in six months, but a lot more may be
possible in just three or four years," he says.
"That informs much of our strategy: to keep you alive, in good shape,
and functioning well, so that the approaches being worked on now may be
something for you in a few years. Is that a guarantee? No. Is it possible?