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Biological Therapy for Breast Cancer

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HER2-Negative Breast Cancer continued...

In HER2-negative breast cancer, everolimus (Afinitor) can be taken with the drug exemestane in postmenopausal women who have already tried certain other treatments. Afinitor is for certain advanced cancers.  

Other types of antibodies and small molecules that are being studied to fight breast cancer include:

  • Angiogenesis inhibitors. These antibodies prevent the growth of new blood vessels, cutting off the supply of oxygen and nutrients to cancer cells.
  • Signal transduction inhibitors. These antibodies block signals inside the cancer cell that help the cells divide, stopping the cancer from growing.

Side Effects of Biological Therapy

Side effects of biological therapy include allergic reactions, trouble breathing, swelling, nausea, rashes, diarrhea, fever, chills, dizziness, and weakness. Side effects differ from one medicine to another. Talk to your doctor about the side effects to watch for. 

Recognizing a Cancer Emergency

Call your nurse or doctor about your cancer if you have:

  • A temperature greater than 100.4 F. If you have any fever and chills, tell your doctor immediately. If you can't reach your doctor, go to the emergency room.
  • New mouth sores or patches, a swollen tongue, or bleeding gums
  • A dry, burning, scratchy, or "swollen" throat
  • A cough that is new or persistent and makes mucus
  • Feeling the need to urinate more often, feeling stronger urges than usual, burning during urination, or blood in your urine
  • Heartburn, nausea, vomiting, constipation, or diarrhea that lasts longer than 2 or 3 days
  • Blood in your stools


WebMD Medical Reference

Reviewed by Angela Jain on April 07, 2014
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