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Biological Therapy for Breast Cancer

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HER2-Negative Breast Cancer continued...

In HER2-negative breast cancer, everolimus (Afinitor) can be taken with the drug exemestane (Aromasin) in postmenopausal women who have already tried certain other treatments. Everolimus is for certain advanced cancers.

Palbociclib (Ibrance) is taken with the drug letrozole (Femara) and is also meant for postmenopausal women with certain types of advanced breast cancer.  

Other types of antibodies and small molecules that are being studied to fight breast cancer include:

  • Angiogenesis inhibitors. These antibodies prevent the growth of new blood vessels, cutting off the supply of oxygen and nutrients to cancer cells.
  • Signal transduction inhibitors. These antibodies block signals inside the cancer cell that help the cells divide, stopping the cancer from growing.

Side Effects of Biological Therapy

Side effects of biological therapy include allergic reactions, trouble breathing, swelling, nausea, rashes, diarrhea, fever, chills, dizziness, and weakness. Side effects differ from one medicine to another. Talk to your doctor about the side effects to watch for.

Recognizing a Cancer Emergency

Call your nurse or doctor if you have:


WebMD Medical Reference

Reviewed by Jennifer Robinson, MD on April 12, 2015
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