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Breast Cancer Health Center

Medical Reference Related to Breast Cancer

  1. Male Breast Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview

    There are different types of treatment for men with breast cancer. Different types of treatment are available for men with breast cancer. Some treatments are standard (the currently used treatment),and some are being tested in clinical trials. Before starting treatment,patients may want to think about taking part in a clinical trial. A treatment clinical trial is a research study meant to ...

  2. Breast Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Special Populations

    Women with Limited Life Expectancy Achieving balance between the benefits and harms of screening is especially important for women with a life expectancy of no longer than 5 years. Such women might have end-stage renal disease,severe dementia,terminal cancer,or severe functional dependencies in activities of daily living. Early cancer detection and prompt treatment are unlikely to reduce ...

  3. Breast Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Triple-Negative Breast Cancer

    Triple-negative breast cancer (TNBC) is defined as the absence of staining for estrogen receptor,progesterone receptor,and HER2/neu. TNBC is insensitive to some of the most effective therapies available for breast cancer treatment including HER2 -directed therapy such as trastuzumab and endocrine therapies such as tamoxifen or the aromatase inhibitors. Combination cytotoxic chemotherapy ...

  4. Breast Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - nci_ncicdr0000062779-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Breast Cancer Prevention

  5. Male Breast Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

    Sources of further information about Male Breast Cancer Treatment.

  6. Male Breast Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - About This PDQ Summary

    PURPOSE OF THIS SUMMARY This PDQ cancer information summary for health professionals provides comprehensive,peer-reviewed,evidence-based information about the treatment of male breast cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. REVIEWERS AND ...

  7. Breast Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Harms of Screening Mammography

    Mammography screening may be effective in reducing breast cancer mortality in certain populations, but it can pose harm to women who participate. The limitations are best described as false-positives (related to the specificity of the test), overdiagnosis (true-positives that will not become clinically significant), false-negatives (related to the sensitivity of the test), discomfort associated with the test, radiation risk and anxiety.False-Positives Leading to Possible Additional InterventionsThe specificity of mammography (refer to the Breast Cancer Screening Concepts section of this summary for more information) affects the number of additional interventions due to false-positive results. Even though breast cancer is the most common noncutaneous cancer in women, fewer than 5 per 1,000 women actually have the disease when they are screened. Therefore, even with a specificity of 90%, most abnormal mammograms are false-positives.[1] Women with abnormal

  8. Breast Cancer Screening (PDQ®): Screening - Patient Information [NCI] - Questions or Comments About This Summary

    If you have questions or comments about this summary,please send them to Cancer.gov through the Web site’s Contact Form. We can respond only to email messages written in English. ...

  9. Breast Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Overview

    Factors Associated with Increased Risk of Breast Cancer

  10. Genetics of Breast and Ovarian Cancer (PDQ®): Genetics - Health Professional Information [NCI] - Low- and Moderate-Penetrance Genes Associated With Breast and / or Ovarian Cancer

    BackgroundMutations in BRCA1, BRCA2, and the genes involved in other rare syndromes discussed in the High-Penetrance Breast and/or Ovarian Cancer Susceptibility Genes section of this summary account for less than 25% of the familial risk of breast cancer.[1] Despite intensive genetic linkage studies, there do not appear to be other BRCA1/BRCA2-like high-penetrance genes that account for a significant fraction of the remaining multiple-case familial clusters.[2] These observations suggest that the remaining breast cancer susceptibility is polygenic in nature, meaning that a relatively large number of low-penetrance genes are involved.[3] On its own, each low-penetrance locus would be expected to have a relatively small effect on breast cancer risk and would not produce dramatic familial aggregation or influence patient management. However in

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