Breast Cancer Health Center
3 Breast Cancer Gene Tests 'Promising'
Feb. 4, 2008 -- Three breast cancer gene tests may provide insights on recurrence risk and chemotherapy treatment.
So say Johns Hopkins University's Luigi Marchionni, MD, PhD, and colleagues.
They reviewed data on three breast cancer gene tests that are already on the market -- Oncotype DX, MammaPrint, and H/I -- which check activity of various breast cancer-related genes.
Oncotype DX screens 21 genes, MammaPrint screens 70 genes, and H/I screens two genes. The tests aren't marketed for all women; they're geared to breast cancer patients.
The bottom line: The tests provide information, but it's not yet clear how to put that information in context or into practice.
"Although these tests show great promise to improve predictions of prognosis and treatment benefit for early-stage breast cancer, more needs to be learned about the extent of that improvement, in whom they affect, and how they are best incorporated into decision-making about current breast cancer treatment," Marchionni's team writes.
The review appears online today in the Annals of Internal Medicine.
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ENABLEX is a prescription medicine used in adults to treat the following symptoms due to a condition called overactive bladder:
- · having a strong need to go to the bathroom right away (also called "urgency")
- · leaks or wetting accidents (also called "urinary incontinence")
- · having to go to the bathroom too often (also called "urinary frequency")
IMPORTANT SAFETY INFORMATION
You should not take once-daily ENABLEX if you have certain types of stomach problems, glaucoma, or have trouble emptying your bladder. Side effects of ENBLEX include blurred vision, and more commonly dry mouth, constipation, indigestion, and abdominal pain. Use caution when doing certain activities until you know how ENBALEX affects you.
October is National Breast Cancer Awareness Month, and a new study reveals why a high number of women with the disease still prefer to have the entire breast surgically removed instead of just the tumor. It's not always because doctors recommend it.
