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Avastin May Help Fight Early Breast Cancer

Studies May Reopen Discussions About Benefits of Avastin for Breast Cancer

Do the Benefits of Avastin Outweigh Its Risks? continued...

He points out that when both studies narrowed their definition of complete response to mean only invasive cancers that had disappeared from both the breast and the lymph nodes, their results were not statistically significant, meaning they could have occurred by chance. “These studies don’t change anything in my mind, and it should not persuade patients that Avastin can change the biology of the disease,” he says. “I think the FDA decision was very appropriate.”

Buzdar says it may turn out that certain subsets of patients are helped by the drug, “but that still remains to be defined.”

Daly agrees that the studies do little to show how the drug might best be used in breast cancer.

“This just leaves us more confused than ever,” she says.

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