Skip to content

    Breast Cancer Health Center

    Font Size
    A
    A
    A

    Stage IV Breast Cancer Treatment Options

    With stage IV, the breast cancer has spread to other parts of your body. Often the bones, brain, lungs, or liver are affected. Because multiple areas may be involved, focused treatments like surgery or radiation alone may not be enough.

    Treatment of stage IV doesn’t cure the disease. But by shrinking the cancer, it can often slow it down, help you feel better, and let you live longer. Patients with stage IV breast cancer may live for years, but it’s usually life-threatening at some point.

    Recommended Related to Breast Cancer

    Christina Applegate Seeks Early Detection for Breast Cancer

    Cancer didn't catch Christina Applegate unprepared. Because her mother had battled both breast cancer and ovarian cancer, Applegate had been going for regular mammograms since the age of 30. "But when I turned 36, my doctor said that my breasts were just too dense for mammography alone, and he referred me for screening MRIs at Cedars-Sinai Medical Center," she recalls. Just a few months before she learned she herself had breast cancer, the actor got a shocking insight into the struggles faced...

    Read the Christina Applegate Seeks Early Detection for Breast Cancer article > >

    Treatments

    Chemotherapy is often the main treatment for this stage. It can slow down the growth of the cancer. It’s often used in combination with hormone therapy.

    You can get chemo several different ways. You may take pills or liquids, but often the drugs are put right into your veins. Depending on the type of treatment, it may be given in cycles that allow your body breaks in between.

    Hormone therapy can be helpful for women with hormone receptor-positive cancers. That means the cancer needs hormones to grow. In these women, medications can prevent the tumor from getting the hormone. These drugs include tamoxifen for all women and anastrozole (Arimidex), exemestane (Aromasin), and letrozole (Femara) for postmenopausal women. Letrozole is sometimes taken with palbociclib (Ibrance), which slows cancer cell growth.

    Women who haven't reached menopause may consider having their ovaries removed to stop them from making hormones that help cancer grow.

    Targeted therapy is a newer treatment. About 20% of women with breast cancer have too much of a protein known as HER2, and it makes the cancer spread quickly. Women with HER2-positive cancer that has spread often take trastuzumab (Herceptin). It stops the protein from making the cancer cells grow. It may also boost your immune system, giving it the strength to fight the cancer itself. Often, people combine this treatment with chemotherapy. Sometimes doctors prescribe another medication, pertuzumab (Perjeta), to take along with trastuzumab and docetaxel (Taxotere).

    After other treatments, your doctor may prescribe lapatinib (Tykerb) to treat HER2-positive advanced breast cancer. People who were previously treated with trastuzumab and a class of chemotherapy drugs called taxanes may also take ado-trastuzumab emtansine (Kadcyla).

    Today on WebMD

    Breast Cancer Overview
    From mammograms to living after treatment.
    Dealing with breast cancer
    Get answers to your questions.
     
    woman having mammogram
    The 3 latest tips to know.
    woman undergoing breast cancer test
    Most abnormalities aren’t breast cancer.
     
    Resolved To Quit Smoking
    VIDEO
    Breast Cancer Treatments Improving
    Article
     
    Woman getting mammogram
    Article
    Screening Tests for Women
    Article
     
    serious woman
    Article
    Pink badge on woman chest to support breat cancer
    QUIZ
     
    what is your cancer risk
    Article
    breast cancer survivors
    Article