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Treatment Options by Stage

    A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.

    Ductal Carcinoma In Situ (DCIS)

    Recommended Related to Breast Cancer

    About This PDQ Summary

    Purpose of This Summary This PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about breast cancer prevention. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. Reviewers and Updates This summary is reviewed regularly and updated as necessary by the PDQ Screening and Prevention Editorial...

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    Treatment of ductal carcinoma in situ (DCIS) may include the following:

    • Breast-conserving surgery and radiation therapy with or without tamoxifen.
    • Total mastectomy with or without tamoxifen.
    • Breast-conserving surgery without radiation therapy.
    • Clinical trials testing breast-conserving surgery and tamoxifen with or without radiation therapy.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with ductal breast carcinoma in situ. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Lobular Carcinoma In Situ (LCIS)

    Treatment of lobular carcinoma in situ (LCIS) may include the following:

    • Biopsy to diagnose the LCIS followed by regular examinations and regular mammograms to find any changes as early as possible. This is called observation.
    • Tamoxifen to reduce the risk of developing breast cancer.
    • Bilateral prophylactic mastectomy. This treatment choice is sometimes used in women who have a high risk of getting breast cancer. Most surgeons believe that this is a more aggressive treatment than is needed.
    • Clinical trials testing cancer prevention drugs.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with lobular breast carcinoma in situ. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Stage I, Stage II, Stage IIIA, and Operable Stage IIIC Breast Cancer

    Treatment of stage I, stage II, stage IIIA, and operable stage IIIC breast cancer may include the following:

    • Breast-conserving surgery to remove only the cancer and some surrounding breast tissue, followed by lymph node dissection and radiation therapy.
    • Modified radical mastectomy with or without breast reconstruction surgery.
    • Sentinel lymph node biopsy followed by surgery.
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