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Breast Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for Breast Cancer

Table 5. Distant Metastases (M)a

a Reprinted with permission from AJCC: Breast. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 347-76.
M0No clinical or radiographic evidence of distant metastases.
cM0(i+)No clinical or radiographic evidence of distant metastases, but deposits of molecularly or microscopically detected tumor cells in circulating blood, bone marrow, or other nonregional nodal tissue that are ≤0.2 mm in a patient without symptoms or signs of metastases.
M1Distant detectable metastases as determined by classic clinical and radiographic means and/or histologically proven >0.2 mm.
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