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Genetics of Breast and Ovarian Cancer (PDQ®): Genetics - Health Professional Information [NCI] - Changes to This Summary (09 / 04 / 2013)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

High-Penetrance Breast and/or Ovarian Cancer Susceptibility Genes

Recommended Related to Breast Cancer

Soy and Breast Cancer: What's the Link?

To be safe, Jennifer Mukai all but eliminated soy from her diet after being told she had breast cancer in May 2009. Being of Japanese descent and also health conscious, the Seattle interior designer says she was eating a lot of soy in various forms before her diagnosis. “I drank about three-quarters of a cup of soy milk in my coffee twice a day and ate tofu and edamame [soy beans] pretty regularly,” the 44-year-old tells WebMD. “I was also probably getting quite a bit of soy in the meat-substitute...

Read the Soy and Breast Cancer: What's the Link? article > >

Added text about a study of 746 Hispanic patients with a personal or family history of breast cancer and/or ovarian cancer who were examined for the prevalence of BRCA1 and BRCA2 mutations. Deleterious BRCA mutations were identified in 25% of the patients, and a possible founder mutation (BRCA1 ex9-12del) was identified (cited Weitzel et al. as reference 67). Also added text about a population-based cohort of 492 Hispanic women with breast cancer that suggested that the BRCA1 ex9-12 deletion may be a Mexican founder mutation and may represent 10% to 12% of all BRCA1 mutations in similar clinic- and population-based cohorts in the United States.

This summary is written and maintained by the PDQ Cancer Genetics Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: September 04, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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