Skip to content

Breast Cancer Health Center

Font Size

Genetics of Breast and Ovarian Cancer (PDQ®): Genetics - Health Professional Information [NCI] - Changes to This Summary (09 / 04 / 2013)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

High-Penetrance Breast and/or Ovarian Cancer Susceptibility Genes

Recommended Related to Breast Cancer

Patty Jenkins' ‘Pearl’ Spotlights the Personal Side of Breast Cancer

Director Patty Jenkins connected naturally to her new short film, Pearl, one of five intertwined vignettes in the Lifetime Original Movies anthology, Five. The film quintet premieres Oct. 10 as part of Lifetime TV's "Stop Breast Cancer for Life" initiative (www.mylifetime.com/my-lifetime-commitment/breast-cancer). "No matter who you are, no amount of information ensures prevention," Jenkins says. "It's almost hard to find somebody who hasn't had a family member or friend with breast cancer." Jenkins,...

Read the Patty Jenkins' ‘Pearl’ Spotlights the Personal Side of Breast Cancer article > >

Added text about a study of 746 Hispanic patients with a personal or family history of breast cancer and/or ovarian cancer who were examined for the prevalence of BRCA1 and BRCA2 mutations. Deleterious BRCA mutations were identified in 25% of the patients, and a possible founder mutation (BRCA1 ex9-12del) was identified (cited Weitzel et al. as reference 67). Also added text about a population-based cohort of 492 Hispanic women with breast cancer that suggested that the BRCA1 ex9-12 deletion may be a Mexican founder mutation and may represent 10% to 12% of all BRCA1 mutations in similar clinic- and population-based cohorts in the United States.

This summary is written and maintained by the PDQ Cancer Genetics Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http:// cancer .gov or call 1-800-4-CANCER.

    WebMD Public Information from the National Cancer Institute

    Last Updated: September 04, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    1
    Next Article:

    Today on WebMD

    Breast Cancer Overview
    From self-exams and biopsies to reconstruction, we’ve got you covered.
    Dealing with breast cancer
    Get answers to your questions.
     
    woman having mammogram
    Experts don’t agree on all fronts, but you can be your own advocate.
    woman undergoing breast cancer test
    Many women worry. But the truth? Most abnormalities aren’t breast cancer.
     
    Breast Cancer Treatments Improving
    VIDEO
    Resolved To Quit Smoking
    SLIDESHOW
     
    Woman getting mammogram
    Article
    Screening Tests for Women
    SLIDESHOW
     
    ovarian cancer overview slideshow
    SLIDESHOW
    serious woman
    Article
     
    what is your cancer risk
    HEALTH CHECK
    10 Ways to Revitalize Slideshow
    SLIDESHOW