Breast Cancer Health Center
Inflammatory Breast Cancer - Topic Overview
What is inflammatory breast cancer?
Inflammatory breast cancer is a rare, fast-growing type of breast cancer. It is often called IBC for short.
Unlike other breast cancers, this type of cancer may not cause a lump in the breast. So regular breast exams and mammograms often fail to catch it early. Because it grows so fast, it usually has spread by the time it is diagnosed.
What causes inflammatory breast cancer?
In this type of cancer, the cancer cells often do not form lumps in the breast. Instead, the cancer cells block the lymph vessels that normally keep lymph fluid moving in the breast.
When the normal flow of lymph fluid is blocked, it
can make the breast look swollen and red and feel warm, as if it were
infected
. The swelling may cause lots of tiny dimples
in the skin. Sometimes it causes a lump that grows quickly, but you can have
inflammatory breast cancer without having a lump in your breast.
What are the symptoms?
Inflammatory breast cancer can cause one or more of these symptoms:
- A breast that is swollen, red, and warm
- A breast that is tender or painful
- An area of itching in the breast
- A recent change in the nipple. Sometimes the nipple pulls back into the breast instead of pointing outward. This is called a retracted nipple.
- A change in the skin, especially an area that looks thick and pitted, like an orange peel. Sometimes there are ridges in the skin and small bumps that look like a rash or hives.
- An area of the breast that looks bruised
- Swollen lymph glands (lymph nodes) in the armpit
- One or more lumps in the breast
How is inflammatory breast cancer diagnosed?
A biopsy is needed to diagnose this cancer. During a biopsy, the doctor takes a sample of the breast or the breast skin. The sample is looked at in a lab to see if it contains cancer cells.
It’s very important to diagnose inflammatory breast cancer quickly so that treatment can begin. But because it is rare and usually doesn't make a lump, doctors may not recognize the symptoms right away. The cancer is often mistaken for other problems, like spider bites, an allergic reaction, or mastitis, which is a breast infection that is usually treated with antibiotics.
Antibiotics do not help inflammatory breast cancer. If your doctor has given you antibiotics and your symptoms do not seem to be getting better after a week, call your doctor.
After a biopsy shows that you have this type of cancer, your doctor will order more tests-such as a mammogram, a bone scan, or a CAT scan-to see if the cancer has spread.
How is it treated?
WebMD Medical Reference from Healthwise
Inflammatory Breast Cancer Topics
VIVELLE-DOT (estradiol transdermal system) IS AVAILABLE BY PRESCRPTION ONLY.
INDICATION
Vivelle-Dot is used after menopause to: reduce moderate to severe hot flashes; treat moderate to severe dryness, itching and burning in or around the vagina; help reduce your chances of getting osteoporosis (thin weak bones); and treat certain conditions in which a young woman's ovaries do not produce enough estrogens naturally. Vivelle-Dot 0.025 mg/day is only used to prevent osteoporosis from menopause. If you use Vivelle-Dot only to treat your dryness, itching, and burning in and around your vagina or if you use Vivelle-Dot only to prevent osteoporosis from menopause, talk with your healthcare professional about whether a different treatment or medicine without estrogens might be better for you.
IMPORTANT SAFETY INFORMATION
Estrogens increase the chances of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are taking estrogens. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb).
Do not use estrogens with or without progestins to prevent heart disease, heart attacks, or strokes. Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with progestins may increase your risk of dementia (decline in memory and thinking skills).
Vivelle-Dot should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack in the recent past (for example, in the past year); currently have or have had blood clots; currently have or have had liver problems; or think you may be, or know that you are, pregnant.
The most common side effects that may occur with Vivelle-Dot are headache, breast tenderness, and back pain.
You and your healthcare professional should talk regularly about whether you still need treatment with Vivelle-Dot.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information for Vivelle-Dot.

