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Breast Cancer Health Center

Understanding Breast Cancer -- Diagnosis & Treatment

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What Are the Treatments for Breast Cancer? continued...

For breast cancer that has metastasized and for breast cancer that has come back, chemotherapy and hormone therapy are the main treatments. Hormone therapy may also be beneficial for cancers that are hormone-responsive. In addition, biologic modifiers such as trastuzumab (Herceptin) may be useful in helping patients whose cancer has an excess of a particular protein called HER2 that causes the cells to divide and grow more aggressively. Surgery may still be an option depending upon the site of recurrence and the extent of other sites of disease.

Chemotherapy for Breast Cancer

When breast cancer is limited to the breast or lymph nodes, adjuvant chemotherapy may be given after a lumpectomy or mastectomy. This is done to help reduce the chance of breast cancer coming back.

If the breast tumor is large, chemotherapy or hormone therapy may be given before surgery to shrink the tumor so it can be removed more easily, or a lumpectomy can be performed instead of a mastectomy.

Chemotherapy or hormone therapy may also be given as the main treatment for women whose cancer has spread to parts of the body outside of the breast and lymph nodes.

Radiation Therapy for Breast Cancer

Radiation therapy is usually given after a lumpectomy and sometimes after a mastectomy to reduce the risk of cancer coming back in the same breast. The radiation treatments generally start several weeks after the surgery so the area has some time to heal. If your doctor recommends chemotherapy along with radiation therapy, the chemotherapy should be given before you start radiation therapy.

The type of breast cancer radiation that most people are familiar with is called external beam radiation. It's also the type most commonly used in cases of breast cancer. External beam radiation works by focusing a beam of radiation from a machine to its target, the area of the body affected by cancer.

The other type of breast cancer radiation is called brachytherapy. This type delivers radiation to the cancer internally using an implant. In the case of breast cancer, radioactive seeds or pellets -- as small as grains of rice -- are placed inside the breast near the cancer. Brachytherapy can be used alone or with external beam radiation. Tumor size, location, and other factors will determine if someone is a candidate for this type of radiation.

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