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    Adenoid Cystic Carcinoma

    Important
    It is possible that the main title of the report Adenoid Cystic Carcinoma is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    • ACC
    • Adenocystic Carcinoma
    • Cribriform Carcinoma
    • Cylindroma

    Disorder Subdivisions

    • None

    General Discussion

    This disease entry was made possible due to the generosity of the Kathleen Keany Memorial Foundation, 8502 East Chapman Avenue, Suite 195, Orange, CA 92869, (714) 538-6920.

    Adenoid cystic carcinoma (ACC) is a relatively rare form of cancer that most commonly develops in the salivary glands or other regions of the head and neck. In some cases, ACC may arise in other primary sites, such as the skin; the breast; the neck of the uterus (cervix) in females, the prostate gland in males; or other areas.

    The term "cancer" refers to a group of diseases characterized by abnormal, uncontrolled cellular growth that invades surrounding tissues and may spread (metastasize) to distant bodily tissues or organs via the bloodstream, the lymphatic system, or other means. Different forms of cancer, including adenoid cystic carcinoma, may be classified based upon the cell type involved, the specific nature of the malignancy, the tissues or organs affected, and the disease's clinical course.

    ACC tumors are characterized by a distinctive pattern in which abnormal "nests" or cords of certain cells (epithelial cells) surround and/or infiltrate ducts or glandular structures within the affected organ. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes (hyaline membranes). Such characteristics are apparent during microscopic evaluation of the tumor cells. ACC is considered a low-grade malignancy that has a history of slow growth, but tends to be aggressively invasive and to infiltrate nearby lymph nodes as well as the "sheaths" or coatings surrounding nerve fibers (perineural spaces). This form of cancer may have a tendency to recur later at the site where it first developed (local recurrence) and to spread to distant bodily sites, particularly the lungs, potentially resulting in life-threatening complications.

    Resources

    American Cancer Society, Inc.
    250 Williams NW St
    Ste 6000
    Atlanta, GA 30303
    USA
    Tel: (404)320-3333
    Tel: (800)227-2345
    TDD: (866)228-4327
    Internet: http://www.cancer.org

    National Cancer Institute
    6116 Executive Blvd Suite 300
    Bethesda, MD 20892-8322
    USA
    Tel: (301)435-3848
    Tel: (800)422-6237
    TDD: (800)332-8615
    Email: cancergovstaff@mail.nih.gov
    Internet: http://www.cancer.gov

    National Coalition for Cancer Survivorship
    1010 Wayne Avenue
    7th Floor
    Silver Spring, MD 20910
    Tel: (301)650-9127
    Fax: (301)565-9670
    Tel: (888)650-9127
    Email: info@canceradvocacy.org
    Internet: http://www.canceradvocacy.org/

    Cancer Hope Network
    2 North Road
    Suite A
    Chester, NJ 07930
    Tel: (908)879-4039
    Fax: (908)879-6518
    Tel: (800)552-4366
    Email: info@cancerhopenetwork.org
    Internet: http://www.cancerhopenetwork.org

    Support for People with Oral and Head and Neck Cancer, Inc.
    P.O. Box 53
    Locust Valley, NY 11560-0053
    USA
    Tel: (516)759-5333
    Fax: (516)671-8794
    Tel: (800)377-0928
    Email: info@spohnc.org
    Internet: http://www.spohnc.org

    OncoLink: The University of Pennsylvania Cancer Center Resource
    3400 Spruce Street
    2 Donner
    Philadelphia, PA 19104-4283
    USA
    Tel: (215)349-8895
    Fax: (215)349-5445
    Email: hampshire@uphs.upenn.edu
    Internet: http://www.oncolink.upenn.edu

    Association of Community Cancer Centers
    11600 Nebel Street, Suite 201
    Rockville, MD 20852-2557
    Tel: (301)984-9496
    Fax: (301)770-1949
    Internet: http://www.accc-cancer.org

    Canadian Cancer Society
    55 St. Clair Avenue West Suite 500
    Toronto, M4V 2Y7
    Canada
    Tel: 4164885400
    Fax: 4164882872
    Tel: 8002688874
    Email: webmaster@ontario.cancer.ca
    Internet: http://www.cancer.ca/

    International Cancer Alliance for Research and Education (ICARE)
    4853 Cordell Avenue
    Suite 14
    Bethesda, MD 20814
    Tel: (301)656-3461
    Fax: (301)654-8684
    Tel: (800)422-7361
    Email: info@icare.org
    Internet: http://www.icare.org

    Adenoid Cystic Carcinoma Organization International
    P.O. Box 112186
    Tacoma, WA 98411
    USA
    Tel: (888)223-7983
    Email: info@accoi.org
    Internet: http://www.accoi.org

    Rare Cancer Alliance
    1649 North Pacana Way
    Green Valley, AZ 85614
    USA
    Internet: http://www.rare-cancer.org

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    Friends of Cancer Research
    1800 M Street NW
    Suite 1050 South
    Washington, DC 22202
    Tel: (202)944-6700
    Email: info@focr.org
    Internet: http://www.focr.org

    Adenoid Cystic Carcinoma Research Foundation
    P.O. Box 442
    Needham, MA 02494
    Tel: (781)248-9699
    Email: info@accrf.org
    Internet: http://www.accrf.org

    Cancer.Net
    American Society of Clinical Oncology
    2318 Mill Road Suite 800
    Alexandria, VA 22314
    Tel: (571)483-1780
    Fax: (571)366-9537
    Tel: (888)651-3038
    Email: contactus@cancer.net
    Internet: http://www.cancer.net/

    Cancer Support Community
    1050 17th St NW Suite 500
    Washington, DC 20036
    Tel: (202)659-9709
    Fax: (202)974-7999
    Tel: (888)793-9355
    Internet: http://www.cancersupportcommunity.org/

    Lance Armstrong Foundation
    2201 E. Sixth Street
    Austin, TX 78702
    Tel: (512)236-8820
    Fax: (512)236-8482
    Tel: (877)236-8820
    Email: media@livestrong.org
    Internet: http://www.livestrong.org

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 3/31/2009
    Copyright 1999, 2001, 2004 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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