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    Bladder Cancer Health Center

    Medical Reference Related to Bladder Cancer

    1. Urethral Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062875-nci-header

      This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Bladder and Other Urothelial Cancers Screening

    2. Bladder Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

      Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

    3. Urethral Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Urethral Cancer Associated With Invasive Bladder Cancer

      Approximately 10% (range, 4%–17%) of patients who undergo cystectomy for bladder cancer can be expected to have or to later develop clinical neoplasm of the urethra distal to the urogenital diaphragm. Factors associated with the risk of urethral recurrence after cystectomy include:[1,2]Tumor multiplicity.Papillary pattern.Carcinoma in situ.Tumor location at the bladder neck.Prostatic urethral mucosal or stromal involvement.The benefits of urethrectomy at the time of cystectomy need to be weighed against the morbidity factors, which include added operating time, hemorrhage, and the potential for perineal hernia. Tumors found incidentally on pathologic examination are much more likely to be superficial or in situ in contrast to those that present with clinical symptoms at a later date when the likelihood of invasion within the corporal bodies is high. The former lesions are often curable, and the latter are only rarely so. Indications for urethrectomy in continuity with

    4. Bladder Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

      Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

    5. Bladder Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

      A link to a list of current clinical trials is included for each treatment section. For some types or stages of cancer, there may not be any trials listed. Check with your doctor for clinical trials that are not listed here but may be right for you.Stage 0 (Papillary Carcinoma and Carcinoma in Situ)Treatment of stage 0 may include the following:Transurethral resection with fulguration.Transurethral resection with fulguration followed by intravesical biologic therapy or chemotherapy.Segmental cystectomy.Radical cystectomy.A clinical trial of photodynamic therapy.A clinical trial of biologic therapy.A clinical trial of chemoprevention therapy given after treatment so the condition will not recur (come back).Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 bladder cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of

    6. Urethral Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062908-nci-header

      This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Bladder Cancer Treatment

    7. Bladder Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

      Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

    8. Urethral Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to This Summary (10 / 21 / 2014)

      The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above. Editorial changes were made to this summary.

    9. Bladder Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stages II and III Bladder Cancer Treatment

      Standard Treatment Options for Stages II and III Bladder CancerStandard treatment options for stage II bladder cancer and stage III bladder cancer include the following:Radical cystectomy.Neoadjuvant combination chemotherapy followed by radical cystectomy.External-beam radiation therapy (EBRT) with or without concomitant chemotherapy.Segmental cystectomy (in selected patients).Transurethral resection (TUR) with fulguration (in selected patients).The most common treatments for muscle-invasive bladder cancer are radical cystectomy and radiation therapy. There is no strong evidence from randomized controlled trials to determine whether surgery or radiation therapy is more effective. There is strong evidence that both therapies become more effective when combined with chemotherapy. At the present time, the treatments with the highest level of evidence supporting their effectiveness are radical cystectomy preceded by multiagent cisplatin-based chemotherapy and radiation therapy

    10. Bladder Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage IV Bladder Cancer Treatment

      Currently, only a small fraction of patients with stage IV bladder cancer can be cured and for many patients, the emphasis is on palliation of symptoms. The potential for cure is restricted to patients with stage IV disease with involvement of pelvic organs by direct extension or metastases to regional lymph nodes.[1]Standard Treatment Options for Stage IV Bladder CancerStandard treatment options for patients with T4b, N0, M0 or any T, N1–N3, M0 diseaseTreatment options for patients with T4b, N0, M0 or any T, N1–N3, M0 disease include the following:Chemotherapy alone.Radical cystectomy.Radical cystectomy followed by chemotherapy.Radical cystectomy alone.External-beam radiation therapy (EBRT) with or without concomitant chemotherapy.Urinary diversion or cystectomy for palliation.Chemotherapy aloneCisplatin-based combination chemotherapy regimens are the standard of care for stage IV bladder cancer.[2,3,4,5,6] The only chemotherapy regimens that have been

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