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Many different treatments can help if your cancer has spread to bone, commonly called bone metastasis. Treatment cannot cure bone metastasis. But it can relieve pain, help prevent complications, and improve your quality of life.

Doctors use two types of treatments for metastatic cancer in the bones. Systemic treatments can reach cancer cells throughout the body. Local treatments directly target the cancer in the bone.

The treatment you get will depend upon:

  • Where your cancer started, and the kind of primary tumor you have
  • Which bones the cancer has invaded
  • The extent of damage to the bones
  • Which types of treatment you already have had
  • Your overall health

Read on for an overview of treatments commonly used for bone metastases, or bone "mets." If a treatment doesn't ease your pain and other symptoms, be sure to let your doctor know. You may find that other approaches work better for you.


Chemotherapy is a common systemic treatment for bone metastasis. Your doctor will use a type of chemo that is effective against your primary tumor. So, if you have metastatic lung cancer, for example, your doctor will use drugs that are effective against lung cancer.

How it works. Anti-cancer drugs target and curb cancer growth. In most cases, you take chemo by mouth or through a vein (by IV). This can often shrink the tumors, which will ease your pain and help you feel better.

Possible side effects. Chemo can kill normal cells in addition to cancer cells. The side effects you might have will depend on:

  • The type and amount of drugs you take
  • The length of your treatment

Common side effects of chemotherapy include:

Your doctor can help you prevent or manage these. Most side effects go away once you stop treatment.

Hormone Therapy


This group of drugs works best in cases where metastasis is weakening the bone.

How it works. You receive bisphosphonates by IV infusion every 3 to 4 weeks. These drugs help with bone metastasis by:

  • Slowing bone damage and reducing the risk of bone fractures
  • Easing bone pain
  • Reducing high levels of calcium in the blood

How Cancer Spreads to Bones

See what bone metastasis does to your bones, and how to fight back.
View slideshow