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    Glioblastoma Multiforme

    Important
    It is possible that the main title of the report Glioblastoma Multiforme is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

    Synonyms

    Disorder Subdivisions

    • None

    General Discussion

    Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor. These tumors are often aggressive and infiltrate surrounding brain tissue. GBMs arise from glial cells, which are cells that form the tissue that surrounds and protects other nerve cells found within the brain and spinal cord. GBMs are mainly composed of star-shaped glial cells known as astrocytes. The general term glioma includes any type of brain tumor such as astrocytoma and oligodendroglioma that arise from glial cells.

    Astrocytomas are classified according to a grading system developed by the World Health Organization (WHO). Astrocytomas come in four grades based upon how fast the cells are reproducing and that likelihood that they will infiltrate nearby tissue. Grades I or II astrocytomas are nonmalignant and may be referred to as low-grade. Grades III and IV astrocytomas are malignant and may be referred to as high-grade astrocytomas. Grade III astrocytomas are known as anaplastic astrocytomas. Grade IV astrocytomas are known as glioblastoma multiforme.

    Resources

    American Brain Tumor Association
    8550 W. Bryn Mawr Avenue, Suite 550
    Chicago, IL 60631
    USA
    Tel: (773)577-8750
    Fax: (773)577-8738
    Tel: (800)886-2282
    Email: info@abta.org
    Internet: http://www.abta.org

    American Childhood Cancer Organization
    10920 Connecticut Ave
    Suite A
    Kensington, MD 20895
    Tel: (301)962-3520
    Fax: (301)962-3521
    Tel: (800)366-2223
    Email: staff@acco.org
    Internet: http://www.candlelighters.org

    American Cancer Society, Inc.
    250 Williams NW St
    Ste 6000
    Atlanta, GA 30303
    USA
    Tel: (404)320-3333
    Tel: (800)227-2345
    TDD: (866)228-4327
    Internet: http://www.cancer.org

    Harvard Brain Tissue Resource Center
    McLean Hospital
    115 Mill Street
    Belmont, MA 02178
    Tel: (617)855-2400
    Fax: (617)855-3199
    Tel: (800)272-4622
    Email: hbtrc@mclean.harvard.edu
    Internet: http://www.brainbank.mclean.org

    National Cancer Institute
    6116 Executive Blvd Suite 300
    Bethesda, MD 20892-8322
    USA
    Tel: (301)435-3848
    Tel: (800)422-6237
    TDD: (800)332-8615
    Email: cancergovstaff@mail.nih.gov
    Internet: http://www.cancer.gov

    Children's Brain Tumor Foundation
    274 Madison Avenue, Suite 1004
    New York, NY 10016
    United States
    Tel: (212)448-1595
    Fax: (212)448-1022
    Tel: (866)228-4673
    Email: info@cbtf.org
    Internet: http://www.cbtf.org

    Brain Tumor Foundation for Children, Inc.
    6065 Roswell Road Suite 505
    Atlanta, GA 30328-4015
    USA
    Tel: (404)252-4107
    Fax: (404)252-4108
    Email: info@braintumorkids.org
    Internet: http://www.braintumorkids.org

    Genetic and Rare Diseases (GARD) Information Center
    PO Box 8126
    Gaithersburg, MD 20898-8126
    Tel: (301)251-4925
    Fax: (301)251-4911
    Tel: (888)205-2311
    TDD: (888)205-3223
    Internet: http://rarediseases.info.nih.gov/GARD/

    Pediatric Brain Tumor Foundation
    302 Ridgefield Court
    Asheville, NC 28806
    Tel: (828)665-6891
    Fax: (828)665-6894
    Tel: (800)253-6530
    Email: pbtfus@pbtfus.org
    Internet: http://www.pbtfus.org

    Friends of Cancer Research
    1800 M Street NW
    Suite 1050 South
    Washington, DC 22202
    Tel: (202)944-6700
    Email: info@focr.org
    Internet: http://www.focr.org

    Cancer Support Community
    1050 17th St NW Suite 500
    Washington, DC 20036
    Tel: (202)659-9709
    Fax: (202)974-7999
    Tel: (888)793-9355
    Internet: http://www.cancersupportcommunity.org/

    Lance Armstrong Foundation
    2201 E. Sixth Street
    Austin, TX 78702
    Tel: (512)236-8820
    Fax: (512)236-8482
    Tel: (877)236-8820
    Email: media@livestrong.org
    Internet: http://www.livestrong.org

    National Brain Tumor Society
    55 Chapel Street
    Suite 200
    Newton, MA 02458
    Tel: (617)924-9997
    Fax: (617)924-9998
    Tel: (800) 770-8287
    Email: info@braintumor.org
    Internet: http://www.braintumor.org

    For a Complete Report:

    This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

    The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

    It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

    This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

    For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

    Last Updated: 5/12/2009
    Copyright 1986, 1987, 1988, 1989, 1996, 1997, 1998, 1999, 2000, 2002, 2004, 2007 National Organization for Rare Disorders, Inc.

    WebMD Medical Reference from the National Organization for Rare Disorders

    Last Updated: May 28, 2015
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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