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Brain Cancer Health Center

Medical Reference Related to Brain Cancer

  1. nci_ncicdr0000062795-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Neuroblastoma Screening

  2. General Information About Pituitary Tumors

    Pituitary tumors represent from 10% to 25% of all intracranial neoplasms. Depending on the study cited, pituitary tumors can be classified into three groups according to their biological behavior:[1,2]Benign adenoma.Invasive adenoma.Carcinoma. Adenomas comprise the largest portion of pituitary neoplasms with an overall estimated prevalence of approximately 17%. Only a minority of adenomas are symptomatic.[3] In addition, pituitary adenomas may be distinguished anatomically as intrapituitary, intrasellar, diffuse, and invasive.[4] Invasive adenomas, which account for approximately 35% of all pituitary neoplasms, may invade the dura mater, cranial bone, or sphenoid sinus.[5] Carcinomas account for 0.1% to 0.2% of all pituitary tumors.[6,7]Clinical PresentationThe most characteristic-presenting features of pituitary adenomas include inappropriate pituitary hormone secretion and visual field deficits.[8]Rare signs and symptoms of pituitary disease include:[8]Cranial nerve palsies.Temporal

  3. Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  4. Treatment of High-Risk Neuroblastoma

    The Children's Oncology Group (COG) high-risk group assignment criteria are described in Table 8.Table 8. Children's Oncology Group (COG) Neuroblastoma High-Risk Group Assignment Schema Used for COG-P9641 and COG-A3961 StudiesaINSS StageAgeMYCNStatusINPC ClassificationDNA PloidybINPC = International Neuroblastoma Pathologic Classification; INSS = International Neuroblastoma Staging System.a The COG-P9641 and COG-A3961 trials established the current standard of care for neuroblastoma patients in terms of risk group assignment and treatment strategies.b DNA Ploidy: DNA Index (DI) > 1 is favorable, DI = 1 is unfavorable; hypodiploid tumors (with DI 1 (DI < 1 [hypodiploid] to be considered favorable ploidy).c INSS stage 2A/2B symptomatic patients with spinal cord compression, neurologic deficits, or other symptoms are treated with immediate chemotherapy for four cycles.d INSS stage 3 or stage 4 patients with clinical symptoms

  5. Questions or Comments About This Summary

    If you have questions or comments about this summary, please send them to Cancer.gov through the Web site's Contact Form. We can respond only to email messages written in English.

  6. Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  7. Stage Information and Treatment of Newly Diagnosed and Recurrent Childhood Spinal Cord Tumors

    There is no uniformly accepted staging system for childhood primary spinal cord tumors. These tumors are classified and treated based on their location within the spinal cord and histology. Refer to one of the following PDQ summaries for more information on the staging and treatment of newly diagnosed and recurrent childhood spinal cord tumors:Childhood Astrocytomas Treatment.Childhood Central Nervous System Embryonal Tumors Treatment.Childhood Ependymoma Treatment.In general, at the time of recurrence, low-grade spinal cord glial tumors can be treated with re-resection with or without the use of radiation therapy. Recurrent low-grade and high-grade tumors that cannot be re-resected can be treated on protocols designed for histologically similar brain tumors.

  8. Glioblastoma Multiforme

    Important It is possible that the main title of the report Glioblastoma Multiforme is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report. ...

  9. Spinocerebellar Ataxia with Axonal Neuropathy

    SCAN1 is a neurodegenerative disorder that is inherited in an autosomal recessive pattern. Spinocerebellar ataxia with axonal neuropathy (SCAN1) is characterized by late childhood-onset of a slowly progressive cerebellar ataxia,followed by areflexia and signs of peripheral neuropathy. Gaze nystagmus and cerebellar dysarthria usually develop after the onset of ataxic gait. As the disease ...

  10. Changes to this Summary (08 / 07 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.General InformationAdded text to state that the presence of the H3F3A K27M mutation occurs exclusively in diffuse high-grade pediatric astrocytomas (cited Gielen et al. as reference 35).Treatment of Childhood Low-Grade AstrocytomasAdded Gnekow et al. as reference 28.Added text to state that a multicenter, phase III, placebo-controlled trial of 117 patients confirmed these earlier findings; 35% of the patients in the everolimus group had at least a 50% reduction in the size of the SEGA, versus no reduction in the placebo group (cited Franz et al. as reference 54 and level of evidence 1iDiv).Treatment of Recurrent Childhood Low-Grade AstrocytomasAdded text to state that surveillance imaging will frequently identify asymptomatic recurrences (cited Udaka et al. as reference 4).Added Gnekow et al.

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