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Brain Cancer Health Center

Medical Reference Related to Brain Cancer

  1. Get More Information From NCI

    National Cancer Institute for more cancer information.

  2. Get More Information From NCI

    Sources of further information about Neuroblastoma Screening.

  3. Recurrent Childhood Brain Stem Glioma

    Diffuse Intrinsic Pontine Gliomas Given the dismal prognosis for patients with diffuse intrinsic pontine glioma (DIPG),progression of the pontine lesion is anticipated generally within 1 year from initial radiation therapy. In most cases,biopsy at the time of clinical or radiologic progression is neither necessary nor recommended. To date,no salvage regimen has been shown to extend survival. ...

  4. Prolactin-Producing Pituitary Tumors Treatment

    Standard Treatment Options for Prolactin (PRL)-Producing Pituitary TumorsStandard treatment options for PRL-producing pituitary tumors include the following:Dopamine agonists, such as cabergoline and bromocriptine.[1,2,3,4,5] Surgery (second-line).[1,2]Radiation therapy (occasionally).[1,2]When the pituitary tumor secretes PRL, treatment will depend on tumor size and the symptoms that result from excessive hormone production. Patients with PRL-secreting tumors are treated with surgery and radiation therapy.[1]Most microprolactinomas and macroprolactinomas respond well to medical therapy with ergot-derived dopamine agonists, including bromocriptine and cabergoline.[2] For many patients, cabergoline has a more satisfactory side effect profile than bromocriptine. Cabergoline therapy may be successful in treating patients whose prolactinomas are resistant to bromocriptine or who cannot tolerate bromocriptine, and this treatment has a success rate of more than 90% in patients with newly

  5. Changes to This Summary (03 / 15 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Editorial changes were made to this summary.

  6. Stages of Childhood Brain Stem Glioma

    After the childhood brain stem glioma has been removed,tests are done to find out if there is tumor remaining. The extent or spread of cancer is usually described as stages. For childhood brain stem glioma,the tumors are described by type: Diffuse intrinsic pontine glioma is a tumor that has spread widely throughout the brain stem. Focal or low-grade glioma is a tumor that is localized to ...

  7. Changes to This Summary (01 / 30 / 2013)

    The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.Treatment of Recurrent Childhood EpendymomaAdded Bouffet et al. as reference 8.This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.

  8. Treatment Option Overview

    Many of the improvements in survival in childhood cancer have been made as a result of clinical trials that have attempted to improve on the best available,accepted therapy. Clinical trials in pediatrics are designed to compare new therapy with therapy that is currently accepted as standard. This comparison may be done in a randomized study of two treatment arms or by evaluating a single new ...

  9. Stage Information and Treatment of Newly Diagnosed and Recurrent Childhood Brain Tumors

    There is no uniformly accepted staging system for childhood brain tumors. These tumors are classified and treated based on their histology and location within the brain (Table 1).Table 1. The Staging and Treatment of Newly Diagnosed or Recurrent Tumors According to Type of Tumor or Pathologic SubtypeTumor TypePathologic SubtypeStaging and Treatment of Newly Diagnosed and Recurrent DiseaseCNS = central nervous system.Astrocytomas and Other Tumors of Glial Origin  –Low-Grade AstrocytomasDiffuse fibrillary astrocytomaChildhood Astrocytomas TreatmentGemistocytic astrocytomaOligoastrocytomaOligodendrogliomaPilocytic astrocytomaPilomyxoid astrocytomaPleomorphic xanthoastrocytomaProtoplasmic astrocytomaSubependymal giant cell astrocytoma–High-Grade AstrocytomasAnaplastic astrocytomaChildhood Astrocytomas TreatmentAnaplastic oligoastrocytomaAnaplastic oligodendrogliomaGiant cell glioblastomaGlioblastomaGliomatosis cerebriGliosarcoma Brain Stem

  10. Treatment Option Overview

    The treatments described in this summary are based on the Children’s Oncology Group (COG) Risk Stratification Schema,which is described in the Stage Information section of this summary. The risk of progression of the tumor causing morbidity and mortality is gauged based on the stage of the tumor,the age of the child at diagnosis,and tumor biology. The biological features considered are the ...

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