This astrocytic tumor is classified as a World Health Organization grade I tumor and is often curable. (Refer to the Pilocytic Astrocytoma section in the Classification section of this summary for more information.)
There are different types of treatment for children with craniopharyngioma.
Different types of treatments are available for children with craniopharyngioma. Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with tumors. When clinical trials show that a new treatment is better than the standard treatment,...
Surgery followed by radiation therapy to known or suspected residual tumor.
Treatment options under clinical evaluation:
At recurrence following surgery, patients should be considered for reoperation and radiation therapy if not previously given. Patients who have received radiation therapy should be considered candidates for nitrosourea-based chemotherapies, for temozolomide, or for clinical trials that evaluate new drugs and biological response modifiers.
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with adult pilocytic astrocytoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
Wallner KE, Gonzales MF, Edwards MS, et al.: Treatment results of juvenile pilocytic astrocytoma. J Neurosurg 69 (2): 171-6, 1988.
Shaw EG, Daumas-Duport C, Scheithauer BW, et al.: Radiation therapy in the management of low-grade supratentorial astrocytomas. J Neurosurg 70 (6): 853-61, 1989.
Stüer C, Vilz B, Majores M, et al.: Frequent recurrence and progression in pilocytic astrocytoma in adults. Cancer 110 (12): 2799-808, 2007.