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Cervical Cancer Health Center

Medical Reference Related to Cervical Cancer

  1. Stage IVB Cervical Cancer

    No standard chemotherapy treatment is available for patients with stage IVB cervical cancer that provides substantial palliation. These patients are appropriate candidates for clinical trials testing single agents or combination chemotherapy employing agents listed below or new anticancer treatments in phase I and II clinical trials.[ 1 ] Information about ongoing clinical trials is available ...

  2. Stage IIB Cervical Cancer

    The size of the primary tumor is an important prognostic factor and should be carefully evaluated in choosing optimal therapy.[ 1 ] Survival and local control are better with unilateral rather than bilateral parametrial involvement.[ 2 ] Patients who are surgically staged as part of a clinical trial and are found to have small volume para-aortic nodal disease and controllable pelvic disease may ..

  3. Stage IVA Cervical Cancer

    The size of the primary tumor is an important prognostic factor and should be carefully evaluated in choosing optimal therapy.[ 1 ] After surgical staging,patients found to have small volume para-aortic nodal disease and controllable pelvic disease may be cured with pelvic and para-aortic radiation therapy. Five randomized phase III trials have shown an overall survival advantage for ...

  4. General Information About Endometrial Cancer

    Related Summaries Note: Other PDQ summaries containing information related to endometrial (uterine corpus) cancer include the following: Uterine Sarcoma Treatment Endometrial Cancer Screening Endometrial Cancer Prevention Statistics Note: Estimated new cases and deaths from endometrial (uterine corpus) cancer in the United States in 2010:[ 1 ] New cases: 43,470. Deaths: 7,950. Cancer of the ...

  5. Treatment Option Overview

    There are different types of treatment for patients with cervical cancer. Different types of treatment are available for patients with cervical cancer. Some treatments are standard (the currently used treatment),and some are being tested in clinical trials. Before starting treatment,patients may want to think about taking part in a clinical trial. A treatment clinical trial is a research ...

  6. Significance

    Epidemiology of Endometrial Cancer Incidence and Mortality Endometrial cancer is the most common invasive gynecologic cancer in US women,with approximately 40,880 new cases projected to occur in 2005 and an estimated 7,310 women are expected to die of the disease.[ 1 ] Endometrial cancer is primarily a disease of postmenopausal women with a mean age at diagnosis of 60 years.[ 2 ] Age-adjusted ...

  7. Stage Information for Endometrial Cancer

    Note: The American Joint Committee on Cancer has recently published a new edition of the AJCC Cancer Staging Manual,which includes revisions to the staging for this disease. The PDQ Adult Treatment Editorial Board,which is responsible for maintaining this summary,is currently reviewing the new staging to determine the changes that need to be made in the summary. In addition to updating this ...

  8. Questions or Comments About This Summary

    If you have questions or comments about this summary,please send them to Cancer.gov through the Web site’s Contact Form. We can respond only to email messages written in English. ...

  9. Treatment Option Overview

    How gestational trophoblastic tumor is treated There are treatments for all patients with gestational trophoblastic tumor. Two kinds of treatment are used: surgery (taking out the cancer) and chemotherapy (using drugs to kill cancer cells). Radiation therapy (using high-energy x-rays to kill cancer cells) may be used in certain cases to treat cancer that has spread to other parts of the body. .

  10. High-Risk Gestational Trophoblastic Neoplasia (FIGO Score ≥7) Treatment

    Multi-agent chemotherapy is standard for the initial management of high-risk gestational trophoblastic neoplasia (GTN). A systematic literature review revealed only one randomized controlled trial (and no high-quality trials)—conducted in the 1980s—comparing multiagent chemotherapy regimens for high-risk GTN.[1] In the trial, only 42 women were randomly assigned to either a CHAMOMA regimen (i.e., methotrexate, folinic acid, hydroxyurea, dactinomycin, vincristine, melphalan, and doxorubicin) or MAC (i.e., methotrexate, dactinomycin, and chlorambucil).[2] There was substantially more life-threatening toxicity in the CHAMOMA arm and no evidence of higher efficacy. However, there were serious methodologic problems with this trial. It was reportedly designed as an equivalency trial, but owing to the small sample size, the trial was inadequately powered to assess equivalence. In addition, the characteristics of the patients randomly assigned to the two study arms were not

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