Cervical Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Overview
Note: Separate PDQ summaries on Cervical Cancer Prevention,Cervical Cancer Treatment,and Levels of Evidence for Cancer Screening and Prevention Studies are also available. Screening With the Papanicolaou (Pap) Test: Benefits Based on solid evidence,regular screening of appropriate women for cervical cancer with the Pap test reduces mortality from cervical cancer. The benefits of screening ...
Cervical Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Overview
Note: Separate PDQ summaries on Cervical Cancer Screening and Cervical Cancer Treatment are also available. Avoidance of Human Papillomavirus Infection Based on solid evidence,the following measures are effective to avoid human papillomavirus (HPV) infection,and thus cervical cancer: ABSTINENCE FROM SEXUAL ACTIVITY MAGNITUDE OF EFFECT: ABSTINENCE PREVENTS HPV INFECTION. Study Design: Evidence ...
Endometrial Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage I Endometrial Cancer
Standard treatment options: A total hysterectomy and bilateral salpingo-oophorectomy should be done if the tumor: Is well or moderately differentiated.Involves the upper 66% of the corpus.Has negative peritoneal cytology.Is without vascular space invasion.Has less than a 50% myometrial invasion.Selected pelvic lymph nodes may be removed. If they are negative, no postoperative treatment is indicated. Postoperative treatment with a vaginal cylinder is advocated by some clinicians.For all other cases and cell types, a pelvic and selective periaortic node sampling should be combined with the total hysterectomy and bilateral salpingo-oophorectomy, if there are no medical or technical contraindications. One study found that node dissection per se did not significantly add to the overall morbidity from hysterectomy. While the radiation therapy will reduce the incidence of local and regional recurrence, improved survival has not been proven and toxic effects are
Cervical Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Changes to This Summary (05 / 15 / 2013)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.General Information About Cervical CancerUpdated statistics with estimated new cases and deaths for 2013 (cited American Cancer Society as reference 1).Recurrent Cervical CancerThis section was extensively revised.This summary is written and maintained by the PDQ Adult Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.
Uterine Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - About This PDQ Summary
Purpose of This SummaryThis PDQ cancer information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about the treatment of uterine sarcoma. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions.Reviewers and UpdatesThis summary is reviewed regularly and updated as necessary by the PDQ Adult Treatment Editorial Board, which is editorially independent of the National Cancer Institute (NCI). The summary reflects an independent review of the literature and does not represent a policy statement of NCI or the National Institutes of Health (NIH). Board members review recently published articles each month to determine whether an article should:be discussed at a meeting,be cited with text, orreplace or update an existing article that is already cited.Changes to the summaries are made through a consensus process in
Endometrial Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage Information for Endometrial Cancer
Definitions: FIGOThe Féderation Internationale de Gynécologie et d'Obstétrique (FIGO) and the American Joint Committee on Cancer (AJCC) have designated staging to define endometrial cancer; the FIGO system is most commonly used.[1,2]Carcinosarcomas should be staged as carcinoma. FIGO stages are further subdivided by the histologic grade of the tumor, for example, stage IC G2.Table 1. Carcinoma of the EndometriumaStagea Adapted from FIGO Committee on Gynecologic Oncology.b Either G1, G2, or G3 (G = grade).c Endocervical glandular involvement only should be considered as stage I and no longer as stage II.d Positive cytology has to be reported separately without changing the stage.IbTumor confined to the corpus uteri.IAbNo or less than half myometrial invasion.IBbInvasion equal to or more than half of the myometrium.IIbTumor invades cervical stroma but does not extend beyond the uterus.cIIIbLocal and/or regional spread of the tumor.IIIAbTumor invades the serosa of the corpus
Uterine Sarcoma Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage II Uterine Sarcoma
Standard treatment options:Surgery (total abdominal hysterectomy, bilateral salpingo-oophorectomy, and pelvic and periaortic selective lymphadenectomy).Surgery plus pelvic radiation therapy.Surgery plus adjuvant chemotherapy.Surgery plus adjuvant radiation therapy (EORTC-55874).In a nonrandomized, Gynecologic Oncology Group study in patients with stage I and II carcinosarcomas, those who had pelvic radiation therapy had a significant reduction of recurrences within the radiation treatment field but no alteration in survival. One nonrandomized study that predominantly included patients with carcinosarcomas appeared to show benefit for adjuvant therapy with cisplatin and doxorubicin.Current Clinical TrialsCheck for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II uterine sarcoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.General information about clinical
Cervical Cancer Prevention (PDQ®): Prevention - Health Professional Information [NCI] - Questions or Comments About This Summary
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Cervical Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Cervical Cancer
After cervical cancer has been diagnosed, tests are done to find out if cancer cells have spread within the cervix or to other parts of the body. The process used to find out if cancer has spread within the cervix or to other parts of the body is called staging. The information gathered from the staging process determines the stage of the disease. It is important to know the stage in order to plan treatment. The following tests and procedures may be used in the staging process:CT scan (CAT scan): A procedure that makes a series of detailed pictures of areas inside the body, taken from different angles. The pictures are made by a computer linked to an x-ray machine. A dye may be injected into a vein or swallowed to help the organs or tissues show up more clearly. This procedure is also called computed tomography, computerized tomography, or computerized axial tomography.PET scan (positron emission tomography scan): A procedure to find malignant tumor cells in the body. A small amount
Endometrial Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062903-nci-header
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Endometrial Cancer Treatment