Progestin Hormone Therapy for Endometrial Cancer
How It Works
A woman's body makes the hormone
Progestin is the man-made form of progesterone.
It is usually given in pill
Hormone therapy works by blocking the action of hormones and stopping cancer cells from growing.
Why It Is Used
Progestin hormone therapy may be used to slow the growth of
endometrial cancer. This may be done when the cancer has spread to other parts of the body. Or it may be done for a young woman with early-stage cancer so she can become pregnant in the future.
How Well It Works
Progestin hormone therapy has been shown to slow cancer cell growth for up to 30% of women
who had advanced endometrial cancer. This therapy also helped to slow
cancer cell growth in women who had endometrial cancer that had come back after treatment.1
Progestin hormone therapy can cause side effects, including:
- Nausea or
- Mild shortness of
- Hot flashes or
- Decreased sex drive.
Serious side effects are rare but may include:
Progestin hormone therapy is also used as an appetite stimulant.
You may experience an increased appetite, which could result in weight
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
What To Think About
Progestin hormone therapy may be given to women who are unable to
have surgery or radiation therapy.
Women who have endometrial cancer that has spread to other parts
of the body may live longer if they receive progestin
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
National Cancer Institute (2010). Endometrial Cancer Treatment (PDQ): Health Professional Version. Available online: http://www.cancer.gov/cancertopics/pdq/treatment/endometrial/healthprofessional.