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    Cervical Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options by Stage

    Carcinoma in Situ (Stage 0)

    Treatment of carcinoma in situ (stage 0) may include the following:

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    Cervical Cancer Clinical Trials

    Major drug companies continually research and develop new medications and treatments, which must be shown to be safe and effective before doctors can prescribe them to patients. Through cervical cancerclinical trials, researchers test the effects of new drugs and treatments on a group of volunteers with cervical cancer. Following a strict protocol and using carefully controlled conditions, researchers evaluate the treatments under development and measure the ability of the new drug or therapy to...

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    • Conization, such as cold-knife conization, loop electrosurgical excision procedure (LEEP), or laser surgery.
    • Hysterectomy for women who cannot or no longer want to have children. This is done only if the tumor cannot be completely removed by conization.
    • Internal radiation therapy for women who cannot have surgery.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage 0 cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stage IA Cervical Cancer

    Stage IA cervical cancer is separated into stage IA1 and IA2.

    Treatment for stage IA1 may include the following:

    • Conization.
    • Total hysterectomy with or without bilateral salpingo-oophorectomy.

    Treatment for stage IA2 may include the following:

    • Modified radical hysterectomy and removal of lymph nodes.
    • Radical trachelectomy.
    • Internal radiation therapy for women who cannot have surgery.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IA cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

    Stages IB and IIA Cervical Cancer

    Treatment of stage IB and stage IIA cervical cancer may include the following:

    • Radiation therapy with chemotherapy given at the same time.
    • Radical hysterectomy and removal of pelvic lymph nodes with or without radiation therapy to the pelvis, plus chemotherapy.
    • Radical trachelectomy.
    • Chemotherapy followed by surgery.
    • Radiation therapy alone.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IB cervical cancer and stage IIA cervical cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. Talk with your doctor about clinical trials that may be right for you. General information about clinical trials is available from the NCI Web site.

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