Skip to content

Cervical Cancer Health Center

Font Size

Endometrial Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Summary of Evidence

Separate PDQ summaries on Endometrial Cancer Prevention; Endometrial Cancer Treatment; and Uterine Sarcoma Treatment are also available.

Transvaginal Ultrasound

Recommended Related to Cervical Cancer

General Information About Cervical Cancer

Cervical cancer is a disease in which malignant (cancer) cells form in the cervix. The cervix is the lower, narrow end of the uterus (the hollow, pear-shaped organ where a fetus grows). The cervix connects the uterus to the vagina (birth canal). Anatomy of the female reproductive system. The organs in the female reproductive system include the uterus, ovaries, fallopian tubes, cervix, and vagina. The uterus has a muscular outer layer called the myometrium and an inner lining called...

Read the General Information About Cervical Cancer article > >

Benefits

There is no evidence that screening by ultrasonography (e.g., endovaginal ultrasound or transvaginal ultrasound) reduces mortality from endometrial cancer. Most cases of endometrial cancer (85%) are diagnosed at low stage because of symptoms, and survival rates are high.

Harms

Based on solid evidence, screening asymptomatic women will result in unnecessary additional biopsies because of false-positive test results. Risks associated with false-positive tests include anxiety and complications from biopsies.

  • Study Design: Evidence obtained from cohort studies.
  • Internal Validity: Fair.
  • Consistency: One study for endometrial biopsy and one study for hysteroscopy.
  • Magnitude of Effects on Health Outcomes: Small negative magnitude.
  • External Validity: Fair.

Endometrial Sampling (Biopsy)

Benefits

There is inadequate evidence that screening by endometrial sampling (i.e., biopsy) reduces mortality from endometrial cancer. Most cases of endometrial cancer (85%) are diagnosed at low stage because of symptoms, and survival rates are high.

Harms

Based on solid evidence, endometrial biopsy may result in discomfort, bleeding, infection, and rarely, uterine perforation.

  • Study Design: Evidence obtained from cohort studies.
  • Internal Validity: Fair.
  • Consistency: One study for endometrial biopsy and one study for hysteroscopy.
  • Magnitude of Effects on Health Outcomes: Small negative magnitude.
  • External Validity: Fair.

    WebMD Public Information from the National Cancer Institute

    Last Updated: September 04, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
    1
    Next Article:

    Today on WebMD

    cancer cell
    HPV is the top cause. Find out more.
    doctor and patient
    Get to know the Symptoms.
     
    sauteed cherry tomatoes
    Fight cancer one plate at a time.
    Lung cancer xray
    See it in pictures, plus read the facts.
     
    Integrative Medicine Cancer Quiz
    QUIZ
    Lifestyle Tips for Depression Slideshow
    SLIDESHOW
     
    Screening Tests for Women
    Slideshow
    what is your cancer risk
    HEALTH CHECK