Skip to content
My WebMD Sign In, Sign Up

Cervical Cancer Health Center

Font Size

Endometrial Cancer Screening (PDQ®): Screening - Health Professional Information [NCI] - Summary of Evidence

Separate PDQ summaries on Endometrial Cancer Prevention; Endometrial Cancer Treatment; and Uterine Sarcoma Treatment are also available.

Transvaginal Ultrasound

Recommended Related to Cervical Cancer

Cellular Classification of Cervical Cancer

Squamous cell (epidermoid) carcinoma comprises approximately 90%, and adenocarcinoma comprises approximately 10% of cervical cancers. Adenosquamous and small cell carcinomas are relatively rare. Primary sarcomas of the cervix have been described occasionally, and malignant lymphomas of the cervix, primary and secondary, have also been reported.

Read the Cellular Classification of Cervical Cancer article > >

Benefits

There is no evidence that screening by ultrasonography (e.g., endovaginal ultrasound or transvaginal ultrasound) reduces mortality from endometrial cancer. Most cases of endometrial cancer (85%) are diagnosed at low stage because of symptoms, and survival rates are high.

Harms

Based on solid evidence, screening asymptomatic women will result in unnecessary additional biopsies because of false-positive test results. Risks associated with false-positive tests include anxiety and complications from biopsies.

  • Study Design: Evidence obtained from cohort studies.
  • Internal Validity: Fair.
  • Consistency: One study for endometrial biopsy and one study for hysteroscopy.
  • Magnitude of Effects on Health Outcomes: Small negative magnitude.
  • External Validity: Fair.

Endometrial Sampling (Biopsy)

Benefits

There is inadequate evidence that screening by endometrial sampling (i.e., biopsy) reduces mortality from endometrial cancer. Most cases of endometrial cancer (85%) are diagnosed at low stage because of symptoms, and survival rates are high.

Harms

Based on solid evidence, endometrial biopsy may result in discomfort, bleeding, infection, and rarely, uterine perforation.

  • Study Design: Evidence obtained from cohort studies.
  • Internal Validity: Fair.
  • Consistency: One study for endometrial biopsy and one study for hysteroscopy.
  • Magnitude of Effects on Health Outcomes: Small negative magnitude.
  • External Validity: Fair.
1

WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Today on WebMD

15 Cancer Symptoms Women Ignore
FEATURE
Dna Test To Help Diagnose Cervical Cancer
VIDEO
 
cancer fighting foods
SLIDESHOW
Could Green Tea Prevent Cervical Cancer
VIDEO
 
Integrative Medicine Cancer Quiz
QUIZ
Lifestyle Tips for Depression Slideshow
SLIDESHOW
 
Screening Tests for Women
Slideshow
what is your cancer risk
HEALTH CHECK