Stage II Endometrial Cancer
Many combinations of preoperative intracavitary and external-beam radiation therapy (EBRT) with hysterectomy and bilateral salpingo-oophorectomy are used for treatment of stage II endometrial cancer, with careful biopsy of the para-aortic nodes at the time of surgery. When microscopic cervical stromal involvement is found, postoperative radiation therapy (EBRT and vaginal radiation therapy) should be used.
Stage IIA
General Information About Cervical Cancer
Cervical cancer is a disease in which malignant (cancer) cells form in the cervix. The cervix is the lower, narrow end of the uterus (the hollow, pear-shaped organ where a fetus grows). The cervix connects the uterus to the vagina (birth canal). Anatomy of the female reproductive system. The organs in the female reproductive system include the uterus, ovaries, fallopian tubes, cervix, and vagina. The uterus has a muscular outer layer called the myometrium and an inner lining called...
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Stage IIA (endocervical glandular involvement only) should be treated the same as stage I disease.
Stage IIB
Standard treatment options:
- Hysterectomy, bilateral salpingo-oophorectomy, and node sampling followed by postoperative radiation therapy.
- Preoperative intracavitary and EBRT followed by hysterectomy and bilateral salpingo-oophorectomy. (A biopsy of the para-aortic nodes should be done at the time of surgery.)
- Radical hysterectomy and pelvic lymphadenectomy in selected cases.
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II endometrial carcinoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
WebMD Public Information from the National Cancer Institute
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