Endometrial Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Recurrent Endometrial Cancer
Biologic agents under evaluation for patients with advanced and recurrent endometrial cancer include:
- Bevacizumab, which was given as a single agent in a phase II trial, and the overall response rate was 13.5%.
- Bevacizumab and temsirolimus.
Clinical trials are appropriate for patients whose disease recurs with distant metastases and who are unresponsive to hormonal therapy. Doxorubicin is the most active anticancer agent employed, with useful but temporary responses obtained in as many as 33% of patients with metastatic disease. Paclitaxel, in combination with platinums or as a single agent, also has significant activity.
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent endometrial carcinoma. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
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