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Gestational Trophoblastic Tumors and Neoplasia Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Epithelioid Trophoblastic Tumor Treatment

These tumors are exceedingly rare. There is little information to guide therapy. However, they are similar in behavior and prognosis to placental-site trophoblastic tumors, so it is reasonable to manage them similarly. (Refer to the Placental-Site Gestational Trophoblastic Tumor Treatment section of this summary for more information.) Only a minority of these tumors are malignant in behavior, but they are not very responsive to systemic therapy. A variety of chemotherapy regimens have been used.[1]

Current Clinical Trials

Recommended Related to Cancer

Treatment of Recurrent Wilms Tumor and Other Childhood Kidney Tumors

Approximately 15% of patients with favorable histology Wilms tumor and 50% of patients with anaplastic Wilms tumor experience recurrence.[1] Historically, the salvage rate for patients with recurrent favorable histology Wilms tumor was 25% to 40%. As a result of modern treatment combinations, the outcome after recurrence has increased up to 60%.[2,3] A number of potential prognostic features influencing outcome post-recurrence have been analyzed, but it is difficult to separate whether these factors...

Read the Treatment of Recurrent Wilms Tumor and Other Childhood Kidney Tumors article > >

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with epithelioid trophoblastic tumor. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.

General information about clinical trials is also available from the NCI Web site.

References:

  1. Palmer JE, Macdonald M, Wells M, et al.: Epithelioid trophoblastic tumor: a review of the literature. J Reprod Med 53 (7): 465-75, 2008.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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