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Common Cancers That Metastasize to the Bones

Treating the Primary Cancer

Most bone metastasis cannot be cured. But treatment can often help relieve symptoms.

The kind of treatment your doctor recommends depends, in part, on what kind of primary cancer you have. Other factors include:

  • Which bones the cancer has invaded
  • Damage to the bones
  • Which treatments you have already had
  • Your state of health

In most cases, doctors treat bone metastasis by treating the primary cancer. Chemotherapy and hormone therapy are examples of treatments commonly used to treat the primary cancer. These are systemic treatments, so they can travel through the bloodstream to reach different parts of the body.

Bone Metastasis Treatments That Can Help You Feel Better

These treatments for the bone can help relieve bone metastasis pain and other symptoms:

  • Radiation therapy. High-energy X-rays can kill cancer cells or slow their growth. Alone or combined with other treatments, this can relieve symptoms of bone mets.
  • Radiopharmaceuticals. Used only for cancer that spreads to bone, these are drugs with radioactive elements. When they are injected, they go to the bone with cancer, killing cancer cells and helping to relieve pain. Low blood counts can be a side effect of this type of therapy.
  • Ablation. In this method, a needle is put directly into a tumor to destroy it with heat, cold, electric current, or alcohol.
  • MRI-Guided Focused Ultrasound. This is a noninvasive procedure that uses ultrasound energy guided by MRI scanning to destroy nerve endings in the area of the tumor. The procedure is used to relieve pain in people who have not had success with radiation or who are unable to be treated with radiation.
  • Bisphosphonates (Aredia and Zometa). Given intravenously (IV) for bone mets, these drugs can reduce damage to the bone, lower the risk of breaks, reduce high blood calcium levels, and lessen pain.
  • Denosumab (Xgeva). Similar to bisphosphonates, this drug is injected to help keep bone from breaking down.
  • Surgery. If bone damage is severe, inserting a supportive rod may be a good option. Other types of surgery may relieve pressure on the spinal cord.
  • Injections of bone cement. These can also strengthen bones to prevent breaks.

Your options for treatment of bone mets may vary depending on your type of cancer, your condition, and tolerance of possible side effects.

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WebMD Medical Reference

Reviewed by Sujana Movva, MD on October 05, 2013

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