Hydrazine sulfate is a chemical compound that has been studied as a treatment for cancer and certain side effects caused by cancer (see Question 1).
Hydrazine sulfate may block the tumor from taking in glucose, which is a type of sugar that tumor cells need to grow (see Question 3).
In randomized clinical trials (a type of research study), hydrazine sulfate did not make tumors shrink or go away. In some randomized trials, however, hydrazine sulfate was reported to be helpful in treating...
That is the mantra and the mission of Stand Up To Cancer (SU2C), the powerhouse advocacy organization founded last fall to raise money to kick-start cancer research. SU2C got off to a splashy, star-studded start with a primetime TV show and fundraiser. Then, just nine months later in May, SU2C had raised enough money to award nearly $74 million to five U.S. cancer research teams (dubbed "dream teams") involving more than 200 researchers from 20 leading institutions. The goal? To work together in a more collaborative way to speed effective new treatments from labs to patients as quickly as possible.
Cancer is still a formidable foe, despite decades of research. The cancer death rate has decreased over the last 15 years, but cancer still claims entirely too many lives: According to the American Cancer Society, more than 560,000 people will die of cancer in 2009.
Taking a multidisciplinary, integrated approach, SU2C proposes to reduce some of these numbers by changing how cancer is researched. To find out more, WebMD talked to three dream team leaders -- find out more about them below -- about their projects, how they plan to use the grant money, and what their work will mean for cancer patients -- with luck, sooner rather than later.
Q: What makes the SU2C research model so different for cancer research?
Cantley: This new approach to funding as well as the researchers' collaborative approach [means] there is sufficient money to put together teams across institutions and still have enough so people can actually reach their goals. We can bring in people who have very strong expertise in different fields to share the money and their expertise.
Dr. Jones: In addition, it allows people to draw up collaborative arrangements with their colleagues and competitors much more quickly than is usually the case. With this initiative, there was a clear urgency to get the right people together as quickly as possible.