Examples of FISH Tests for Cancer
Although the FISH test is often used to analyze genetic abnormalities in breast cancer, it also can provide important information about many other types of cancer.
In the diagnosis of bladder cancer, for example, FISH testing of urinary cells may be more reliable than a standard test that looks for abnormal cells. In addition, FISH may detect bladder cancer recurrences three to six months earlier.
FISH also can identify chromosomal abnormalities in leukemias, including chronic lymphocytic leukemia (CLL) cells, some of which are associated with aggressive forms of the disease. Patients with more aggressive forms of CLL may need urgent treatment while those with less aggressive forms may only require observation.