How It Works
Irinotecan is an antitumor drug that interferes with how cancer
cells multiply. The dose is based on your body size. The type and extent of a
cancer determines the exact dose and schedule for using this drug. Irinotecan
intravenous (IV) drug.
Why It Is Used
Irinotecan is used to treat cancer of the cervix, colon, or rectum.
It may also be used to treat non–small-cell lung cancer.
How Well It Works
Irinotecan is an effective antitumor drug for many
people. But the type and extent of a cancer determines how
effectively this drug slows or stops the growth of cancer cells in the
body. Irinotecan is often used in combination with other chemotherapy drugs, making the other drugs more effective than they are by
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
- Usually the benefits of the medicine are more important than any minor side effects.
- Side effects may go away after you take the medicine for a while.
- If side effects still bother you and you wonder if you should keep taking the medicine, call your doctor. He or she may be able to lower your dose or change your medicine. Do not suddenly quit taking your medicine unless your doctor tells you to.
Call911or other emergency services right away if you have:
Call your doctor if you have:
Common side effects of this medicine include:
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
What To Think About
Irinotecan may cause kidney or liver problems and low blood counts. Your doctor will check and closely watch you for these problems and monitor your blood counts.
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Advice for women
Do not use this medicine if you are pregnant, breast-feeding, or planning to get pregnant. If you need to use this medicine, talk to your doctor about how you can prevent pregnancy.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Libutti SK, et al. (2011). Cancer of the colon. In VT DeVita Jr. et al., eds., DeVita, Hellman and Rosenberg's Cancer: Principles and Practice of Oncology, 9th ed., pp. 1084–1126. Philadelphia: Lippincott Williams and Wilkins.
Primary Medical Reviewer
||E. Gregory Thompson, MD - Internal Medicine
Specialist Medical Reviewer
||Kenneth Bark, MD - Surgery, Colon and Rectal
Current as of
||September 5, 2012