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    Bone Marrow Aspiration and Biopsy

    How It Is Done continued...

    The skin over the aspiration site will be cleaned with a special solution and a medicine (local anesthetic) will be used to numb the area. Then the aspiration needle will be put through your skin and into your bone to reach the bone marrow. You need to lie very still while the sample is taken. The needle is then taken out. More than one sample may be needed, possibly from more than one place on your body, such as from both sides of the pelvic bone.

    A bone marrow biopsy uses a special tool that twists into the bone. It is normal to feel pressure at the site and hear a crunching sound as the tool twists into the bone.

    After the samples have been taken, pressure is put on the site to stop any bleeding. A bandage is put on the area.

    How It Feels

    This procedure may be painful, but only for a few seconds. You may feel a sharp sting and burn when the anesthetic numbs your skin over the aspiration or biopsy site. You may hear a crunching sound and feel pressure and some pain when the needle enters the bone. During an aspiration, you may feel a quick, shooting pain down your leg as the sample is taken.

    The biopsy site may feel stiff or sore for several days after the biopsy. You may have a bruise on the site.

    Risks

    Serious problems from a bone marrow aspiration or biopsy are not common. Problems may include:

    • Bleeding from the biopsy site. People with bleeding problems have a higher chance for this. If you have bleeding problems, pressure will be put on the biopsy site for at least 10 minutes after the biopsy. In rare cases, you may be given a blood product (clotting factor or platelets) in a vein in your arm before the biopsy to prevent bleeding after the biopsy.
    • Infection of skin or the bone (osteomyelitis) at the biopsy site.
    • Injury to your heart, a lung, or a major blood vessel if the sample is taken from the breastbone (sternum). This complication is very rare. Samples are not often taken from the breastbone, so most people do not have to worry about this risk.

    After the biopsy

    WebMD Medical Reference from Healthwise

    Last Updated: November 14, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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