Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Leukemia & Lymphoma

Font Size

High-Risk Procedure Pays Off for Leukemia Patient

WebMD Health News

June 13, 2001 -- "This isn't the way it should be; I'm mad, and I'm going to do something about it!" Chris DeVine, age 30, recalls how he felt in May 1998 when he was diagnosed with leukemia, a cancer affecting blood cells.

But DeVine's treatment options were limited. Bone marrow transplantation for his type of leukemia often succeeds in restoring the primitive stem cells that can grow into normal, mature blood cells, but unless those cells are a close genetic match to the patient's, the body's defense system will usually mount an attack against the unrecognized "invaders." In DeVine's case, his doctors couldn't find a suitable donor.

Using blood from the umbilical cord is a relatively new approach. Normally discarded along with the placenta after birth, cord blood can be collected without risk to mother or baby, shipped frozen, and stored while awaiting transplant. Because stem cells in the cord blood are immature, they are less likely to be rejected than bone marrow.

There's only one catch -- at the time DeVine had to face this decision, virtually all cord blood transplants had been done in children. Researchers were concerned that the tiny amount of blood in each umbilical cord -- only two ounces -- might not be enough to replenish the blood-forming system in an adult, and that more sophisticated immune defenses might increase the risk of rejection.

Before receiving the cord blood, DeVine had to undergo massive doses of radiation and chemotherapy to wipe out his own remaining bone marrow.

"It was really scary," DeVine tells WebMD. "Once they obliterate your bone marrow, it's the point of no return. If the cord blood transplant doesn't take, it's game over."

But one conversation with Mary J. Laughlin, MD, helped put DeVine's mind at ease. She is director of the Allogeneic Transplant Program at Case Western Reserve University and University Hospitals Ireland Cancer Center in Cleveland, and DeVine says he was "really impressed with her confidence."

"Transplantation of cord blood following high-dose chemotherapy and radiation can save the lives of about one-third of our adult patients with life-threatening blood diseases for whom other treatments are likely to fail," Laughlin tells WebMD.

1 | 2 | 3

Today on WebMD

stem cells
What are they and why do we need them?
Lung cancer xray
See it in pictures, plus read the facts.
sauteed cherry tomatoes
Fight cancer one plate at a time.
Ovarian cancer illustration
Do you know the symptoms?
Vitamin D
New Treatments For Non-Hodgkins Lymphoma
Lifestyle Tips for Depression Slideshow
Pets Improve Your Health