Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Cancer Health Center

Font Size

IUDs May Help Treat Endometrial Cancer

Study Shows Intrauterine Device May Treat Women Who Want to Avoid Hysterectomy

Testing IUDs to Treat Cancer continued...

The patients were closely followed during and after treatment, with biopsies and pelvic ultrasounds performed every six months.

Over the course of follow-up, 19 of the 20 patients with AEH had an initial complete response to therapy, with four of these patients relapsing later. Eight of the 14 patients with endometrial cancer had an initial complete response to therapy with two of these patients relapsing. The average time to relapse was three years.

Patients who relapsed were treated with either hysterectomy or another course of IUD/GnRH and all were alive and free of disease at the time the study was published. Nine of the women gave birth following treatment.

The study appears today online in the Annals of Oncology.

Second Opinion

Gynecologic oncologist and pelvic surgeon Elizabeth A. Poynor, MD, of Manhattan’s Lenox Hill Hospital has used progesterone-releasing IUDs to treat older endometrial cancer patients who were not good candidates for surgery and could not tolerate oral hormone therapy.

She has not used the treatment in younger patients, but calls the latest study “promising” and says larger studies are warranted.

“We have used oral progestins as fertility-sparing treatments for about 20 years, and they are effective,” she tells WebMD. “But this is a promising way to deliver the hormone locally, which could certainly benefit some patients.”

Like Minig, she stressed the importance of careful and thorough evaluation of women being considered for the treatment by specialists in gynecologic oncology, including pathologists trained to identify gynecologic tumors.

‘This study included a very carefully selected group of patients,” she says. “Careful selection is important to make sure this treatment is used only in patients whose cancers have not spread.”

1 | 2

Today on WebMD

Colorectal cancer cells
New! I AM Not Cancer Facebook Group
Lung cancer xray
See it in pictures, plus read the facts.
sauteed cherry tomatoes
Fight cancer one plate at a time.
Ovarian cancer illustration
Real Cancer Perspectives
Jennifer Goodman Linn self-portrait
what is your cancer risk
colorectal cancer treatment advances
breast cancer overview slideshow
prostate cancer overview
lung cancer overview slideshow
ovarian cancer overview slideshow
Actor Michael Douglas