Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started
My Medicine

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up

Cancer Health Center

Font Size

Botox Tested on Stomach Cancer in Mice

Preliminary research suggests the wrinkle treatment might silence critical nerves that support tumors


According to the study, the two treatments reduced the number of tumors and their progression while boosting survival and the effects of chemotherapy.

The findings show that "nerves are very important in the development and formation of many organ systems and likely play a very important role in the early growth and spread of tumors," Wang said.

Botox is made from a toxin produced by the bacterium Clostridium botulinum. It is best known for temporarily smoothing wrinkles by paralyzing facial muscles. Doctors also use it to correct crossed eyes, control excessive underarm sweating and overactive bladder, and to treat migraine headaches, according to the National Institutes of Health.

Wang acknowledged there are many caveats to the study. For one thing, silencing the nerves could hurt the functioning of the stomach, although some issues could be fixed. "In the setting of cancer all of these effects are probably minor," Wang said. Also, the treatment wouldn't help with cancer that has spread beyond the stomach, he said.

It's also not clear how much a possible Botox treatment would cost, although the toxin in Botox is fairly cheap compared to the cost of many cancer drugs, he said, and has few side effects. The Botox would be administered through gastroscopy, a noninvasive procedure, and require a hospital stay of a few hours, the researchers said.

Wang said researchers are now testing their approaches in patients in clinical trials. However, Lichtenfeld cautioned that the approach's "impact on cancer treatment remains far from certain."

Results obtained from animal studies are not necessarily replicated in humans. "This would have to be applied in patients before anyone could make any claim about the benefit," Lichtenfeld said.

1 | 2

Today on WebMD

Colorectal cancer cells
New! I AM Not Cancer Facebook Group
Lung cancer xray
See it in pictures, plus read the facts.
sauteed cherry tomatoes
Fight cancer one plate at a time.
Ovarian cancer illustration
Real Cancer Perspectives
Jennifer Goodman Linn self-portrait
what is your cancer risk
colorectal cancer treatment advances
breast cancer overview slideshow
prostate cancer overview
lung cancer overview slideshow
ovarian cancer overview slideshow
Actor Michael Douglas