Treatment for Adult Lymphoblastic Lymphoma
Lymphoblastic lymphoma is a very aggressive form of non-Hodgkin lymphoma (NHL), which often occurs in young patients, but not exclusively. Lymphoblastic lymphoma is commonly associated with large mediastinal masses and has a high predilection for disseminating to bone marrow and the central nervous system (CNS). The treatment paradigms are based on trials for acute lymphoblastic leukemia (ALL) since lymphoblastic lymphoma and ALL are considered different manifestations of the same biologic disease. (Refer to the PDQ summary on Adult Acute Lymphoblastic Leukemia Treatment for more information.) Treatment is usually patterned after ALL. Intensive combination chemotherapy with CNS prophylaxis is the standard treatment of this aggressive histologic type of NHL. Radiation therapy is sometimes given to areas of bulky tumor masses. Since these forms of NHL tend to progress quickly, combination chemotherapy is instituted rapidly once the diagnosis has been confirmed.The most important aspects
Non-Hodgkin’s Lymphoma Clinical Trials
Find clinical trials testing new treatments for non-Hodgkin’s lymphoma.
Non-Hodgkin's Lymphoma - Topic Overview
Learn about non-Hodgkin's lymphoma (NHL), cancer of the cells of the lymphatic system.
Non-Hodgkin's Lymphoma - Symptoms
Symptoms of non-Hodgkin's lymphoma (NHL) depend on the area of the body affected by the disease. The most common symptom is a painless swelling of the lymph nodes in the neck, underarm, or groin.
Non-Hodgkin's Lymphoma - Exams and Tests
If non-Hodgkin's lymphoma (NHL) is suspected, your health professional will ask about your medical history and perform a physical examination. This exam includes checking for enlarged lymph nodes in your neck, underarm, or groin. A tissue sample (biopsy
Non-Hodgkin's Lymphoma - What Happens
In non-Hodgkin's lymphoma (NHL), either abnormal cells in the lymphatic system divide and grow without order or control or old cells do not die normally.
Non-Hodgkin's Lymphoma - When To Call a Doctor
Call your health professional to schedule an appointment if you have had any non-Hodgkin's lymphoma symptoms for longer than 2 weeks.
Non-Hodgkin's Lymphoma - Surgery
Surgery is not used to treat non-Hodgkin's lymphoma. What to think about Because of recent improvements in some tests (such as the CT scan, MRI, and PET scan), exploratory surgery is rarely used to stage NHL.
Non-Hodgkin's Lymphoma - Other Treatment
Radiation therapy is often the treatment of choice for early-stage or nonaggressive (indolent) non-Hodgkin's lymphoma (NHL). Radiation therapy may be used alone or combined with other treatment options.
Non-Hodgkin's Lymphoma - Cause
The cause of non-Hodgkin's lymphoma (NHL) is unknown. The incidence of NHL has continued to increase over the years. It may be caused by a genetic factor and may require a "trigger, " such as exposure to something in the environment, to develop.