Adult Non-Hodgkin Lymphoma Treatment (PDQ®): Treatment - Patient Information [NCI] - General Information About Adult Non-Hodgkin Lymphoma
If cancer is found, the following tests may be done to study the cancer cells:
- Immunohistochemistry study: A laboratory test in which a substance such as an antibody, dye, or radioisotope is added to a sample of cancer tissue to test for certain antigens. This type of study is used to tell the difference between different types of cancer.
- Cytogenetic analysis: A laboratory test in which cells in a sample of tissue are viewed under a microscope to look for certain changes in the chromosomes.
- Immunophenotyping: A process used to identify cells, based on the types of antigens or markers on the surface of the cell. This process is used to diagnose specific types of leukemia and lymphoma by comparing the cancer cells to normal cells of the immune system.
Certain factors affect prognosis (chance of recovery) and treatment options.
The prognosis (chance of recovery) and treatment options depend on the following:
- The stage of the cancer.
- The type of non-Hodgkin lymphoma.
- The amount of lactate dehydrogenase (LDH) in the blood.
- The amount of beta-2-microglobulin in the blood (for Waldenström macroglobulinemia).
- The patient's age and general health.
- Whether the lymphoma has just been diagnosed or has recurred (come back).
For non-Hodgkin lymphoma during pregnancy, the treatment options also depend on:
- The wishes of the patient
- Which trimester of pregnancy the patient is in.
Some types of non-Hodgkin lymphoma spread more quickly than others do. Most non-Hodgkin lymphomas that occur during pregnancy are aggressive. Delaying treatment of aggressive lymphoma until after the baby is born may lessen the mother's chance of survival. Immediate treatment is often recommended, even during pregnancy.