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Non-Hodgkin's Lymphoma

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Childhood Non-Hodgkin Lymphoma Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Childhood Non-Hodgkin Lymphoma

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Treatment of high-stage (stage III or IV) anaplastic large-cell lymphoma in children and adolescents may include the following:

  • Combination chemotherapy.
  • Intrathecal or systemic chemotherapy for cancer in the brain or spinal cord.
  • A clinical trial of new combination chemotherapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage III childhood anaplastic large cell lymphoma and stage IV childhood anaplastic large cell lymphoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Recurrent Childhood Non-Hodgkin Lymphoma

There is no standard treatment for patients with recurrent childhood non-Hodgkin lymphoma.

All patients with recurrent childhood non-Hodgkin lymphoma should be considered for clinical trials of new treatments.

Burkitt lymphoma and diffuse large B-cell lymphoma

Treatment options for recurrent Burkitt lymphoma and diffuse large B-cell lymphoma include:

  • Combination chemotherapy.
  • Combination chemotherapy and targeted therapy with a monoclonal antibody.
  • High-dose chemotherapy with stem cell transplant.

Lymphoblastic lymphoma

Treatment options for recurrent lymphoblastic lymphoma include:

  • Combination chemotherapy.
  • High-dose chemotherapy with stem cell transplant.
  • A clinical trial of targeted therapy (kinase inhibitor) with combination chemotherapy.

Anaplastic large-cell lymphoma

Treatment options for recurrent anaplastic large cell lymphoma include:

  • Chemotherapy with one or more drugs.
  • High-dose chemotherapy with stem cell transplant.
  • A clinical trial of targeted therapy with a tyrosine kinase inhibitor.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent childhood non-Hodgkin lymphoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Lymphoproliferative Disease Associated with a Weakened Immune System

Treatment of lymphoproliferative disease in children and adolescents with weakened immune systems may include the following:

  • Surgery with or without radiation therapy.
  • Combination chemotherapy.
  • Low-dose chemotherapy.
  • A clinical trial of stem cell transplant followed by donor lymphocyte infusion or an infusion of T-cell lymphocytes that have been treated in the laboratory.
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WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
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