Pancreatic Cancer Clinical Trials
WebMD helps pancreatic cancer patients and their loved ones find a clinical trial that may offer a promising new treatment.
Learn about pancreatic cancer from the experts at WebMD.
Understanding Pancreatic Cancer -- Symptoms
A look at the symptoms of pancreatic cancer from the experts at WebMD.
Understanding Pancreatic Cancer -- Diagnosis and Treatment
Learn about the diagnosis and treatment of pancreatic cancer.
Understanding Pancreatic Cancer -- the Basics
Get the basic facts about pancreatic cancer.
WebMD explains the Whipple surgical procedure for pancreatic cancer.
Recurrent Pancreatic Cancer Treatment
Treatment Options for Recurrent Pancreatic CancerTreatment options for recurrent pancreatic cancer include the following:Palliative therapy.Chemotherapy: fluorouracil  or gemcitabine.[2,3,4]Palliative therapyPalliative therapy for recurrent pancreatic cancer includes the following:Palliative surgical bypass procedures such as endoscopic or radiologically placed stents.[5,6]Palliative radiation procedures.Pain relief by celiac axis nerve or intrapleural block (percutaneous).Other palliative medical care alone.ChemotherapyChemotherapy occasionally produces objective antitumor response, but the low percentage of significant responses and lack of survival advantage warrant use of therapies under evaluation.Treatment Options Under Clinical Evaluation for Recurrent Pancreatic CancerTreatment options under clinical evaluation include the following:Phase I and II clinical trials evaluating pharmacologic modulation of fluorinated pyrimidines, new anticancer agents, or biological
Curative surgical excision, by open laparotomy or laparoscopy, is the treatment of choice when possible. The open surgical approach is used if the tumor is suspected to be malignant, since en bloc lymphadenectomy is performed for malignant tumors without distant metastases. Intraoperative ultrasound aids the localization of tumor extent and the relationship to other anatomic structures.Standard treatment options:Single small lesion in head or tail of pancreas:[1,2,3,4]Enucleation, if feasible. Large lesion in the head of the pancreas that is not amenable to enucleation:[1,2,3,4]Pancreaticoduodenectomy.Single large lesion in body/tail:[1,2,3,4]Distal pancreatectomy.Multiple lesions: occur in 10%, often in association with multiple endocrine neoplasia syndrome type 1 (MEN-1):[1,2,3,4]Distal pancreatectomy with enucleation of tumors in the head of the pancreas.Metastatic lesions: lymph nodes or distant sites:[5,6,7,8,9,10,11,12]Resect when possible.Consider radiofrequency or
Get More Information From NCI
Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment