General Information About Pancreatic Cancer
Related Summary Note: Another PDQ summary containing information related to pancreatic cancer includes: Unusual Cancers of Childhood (pancreatic cancer in children) Statistics Note: Estimated new cases and deaths from pancreatic cancer in the United States in 2010:[ 1 ] New cases: 43,140. Deaths: 36,800. Note: Some citations in the text of this section are followed by a level of evidence. The ...
About This PDQ Summary
PURPOSE OF THIS SUMMARY This PDQ cancer information summary for health professionals provides comprehensive,peer-reviewed,evidence-based information about the treatment of pancreatic cancer. It is intended as a resource to inform and assist clinicians who care for cancer patients. It does not provide formal guidelines or recommendations for making health care decisions. REVIEWERS AND UPDATES ...
Stage Information for Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)
Note: The American Joint Committee on Cancer has published the 7th edition of the AJCC Cancer Staging Manual, which for the first time incorporates pancreatic neuroendocrine tumors in the same staging system as pancreatic exocrine tumors. The classification of these tumors as benign versus malignant is not always consistent, so the AJCC recommends that all pancreatic neuroendocrine tumors be staged using this system and reported to cancer registries. It also recommends that the protocol developed by the College of American Pathologists for endocrine pancreatic tumors be used to examine and stage specimens.Definitions of TNMThe American Joint Committee on Cancer has designated staging by TNM classification to define pancreatic neuroendocrine tumors (islet cell tumors).Table 2. Primary Tumor (T)aa Reprinted with permission from AJCC: Exocrine and endocrine pancreas. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer,
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment
Stages of Pancreatic Cancer
Tests and procedures to stage pancreatic cancer are usually done at the same time as diagnosis. The following stages are used for pancreatic cancer: Stage 0 In stage 0,the cancer is found only in the lining of the pancreas. Stage 0 is also called carcinoma in situ. Stage I In stage I,cancer is found only in the pancreas. Stage I is divided into stage IA and stage IB,based on the size of ...
General Information About Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)
Pancreatic neuroendocrine tumors form in hormone-making cells (islet cells) of the pancreas.The pancreas is a gland about 6 inches long that is shaped like a thin pear lying on its side. The wider end of the pancreas is called the head, the middle section is called the body, and the narrow end is called the tail. The pancreas lies behind the stomach and in front of the spine. Anatomy of the pancreas. The pancreas has three areas: head, body, and tail. It is found in the abdomen near the stomach, intestines, and other organs. There are two kinds of cells in the pancreas:Endocrine pancreas cells make several kinds of hormones (chemicals that control the actions of certain cells or organs in the body), such as insulin to control blood sugar. They cluster together in many small groups (islets) throughout the pancreas. Endocrine pancreas cells are also called islet cells or islets of Langerhans. Exocrine pancreas cells make enzymes that are released into the small intestine to help the
Treatment Option Overview
Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) The survival rate of patients with any stage of pancreatic exocrine cancer is ..
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This information summary for health professionals provides comprehensive, peer-reviewed, evidence-based information about cancer.
STANDARD TREATMENT OPTIONS: Single lesion in head of pancreas or single lesion less than 1.0 cm in tail of pancreas: Enucleation,if feasible. Single lesion in body/tail greater than 1.0 cm: Distal pancreatectomy. Multiple lesions: Resect body and tail. Metastatic disease-lymph nodes or distant sites: Resect when possible. Consider radiofrequency or cryosurgical ablation if not resectable. ...
Changes to This Summary (01 / 18 / 2013)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above. Editorial changes were made to this summary.