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Pancreatic Cancer Health Center

Medical Reference Related to Pancreatic Cancer

  1. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Insulinoma

    Curative surgical excision, by open laparotomy or laparoscopy, is the treatment of choice when possible. The open surgical approach is used if the tumor is suspected to be malignant, since en bloc lymphadenectomy is performed for malignant tumors without distant metastases. Intraoperative ultrasound aids the localization of tumor extent and the relationship to other anatomic structures.[1]Standard treatment options:Single small lesion in head or tail of pancreas:[1,2,3,4]Enucleation, if feasible. Large lesion in the head of the pancreas that is not amenable to enucleation:[1,2,3,4]Pancreaticoduodenectomy.Single large lesion in body/tail:[1,2,3,4]Distal pancreatectomy.Multiple lesions: occur in 10%, often in association with multiple endocrine neoplasia syndrome type 1 (MEN-1):[1,2,3,4]Distal pancreatectomy with enucleation of tumors in the head of the pancreas.Metastatic lesions: lymph nodes or distant sites:[5,6,7,8,9,10,11,12]Resect when possible.Consider radiofrequency or

  2. Pancreatic Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  3. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Patient Information [NCI] - nci_ncicdr0000062678-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment

  4. Pancreatic Cancer Treatment (PDQ®): Treatment - Patient Information [NCI] - To Learn More About Pancreatic Cancer

    For more information from the National Cancer Institute about pancreatic cancer, see the following:Pancreatic Cancer Home PageWhat You Need to Know About™ Cancer of the PancreasUnusual Cancers of ChildhoodDrugs Approved for Pancreatic CancerUnderstanding Cancer Series: Targeted Therapies (Advances in Targeted Therapies)Targeted Cancer TherapiesFor general cancer information and other resources from the National Cancer Institute, see the following:What You Need to Know About™ CancerUnderstanding Cancer Series: CancerCancer StagingChemotherapy and You: Support for People With CancerRadiation Therapy and You: Support for People With CancerCoping with Cancer: Supportive and Palliative CareQuestions to Ask Your Doctor About CancerCancer LibraryInformation For Survivors/Caregivers/Advocates

  5. Pancreatic Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Get More Information From NCI

    Call 1-800-4-CANCERFor more information, U.S. residents may call the National Cancer Institute's (NCI's) Cancer Information Service toll-free at 1-800-4-CANCER (1-800-422-6237) Monday through Friday from 8:00 a.m. to 8:00 p.m., Eastern Time. A trained Cancer Information Specialist is available to answer your questions.Chat online The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist. The service is available from 8:00 a.m. to 11:00 p.m. Eastern time, Monday through Friday. Information Specialists can help Internet users find information on NCI Web sites and answer questions about cancer. Write to usFor more information from the NCI, please write to this address:NCI Public Inquiries Office9609 Medical Center Dr. Room 2E532 MSC 9760Bethesda, MD 20892-9760Search the NCI Web siteThe NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support

  6. Pancreatic Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage I and Stage II Pancreatic Cancer Treatment

    Treatment Options for Stages I and II Pancreatic CancerTreatment options for stages I and II pancreatic cancer include the following:Surgery: radical pancreatic resection including:Whipple procedure (pancreaticoduodenal resection).Total pancreatectomy when necessary for adequate margins.Distal pancreatectomy for tumors of the body and tail of the pancreas.[1,2]Postoperative chemoradiation therapy: radical pancreatic resection followed by 5-fluorouracil (5-FU) chemotherapy and radiation therapy.[3,4,5,6,7]Postoperative chemotherapy: radical pancreatic resection followed by chemotherapy (gemcitabine or 5-FU/leucovorin).[8]Surgery Complete resection can yield 5-year survival rates of 18% to 24%, but ultimate control remains poor because of the high incidence of both local and distant tumor recurrence.[9,10,11][Level of evidence: 3iA]Approximately 20% of patients present with pancreatic cancer amenable to local surgical resection, with operative mortality rates of

  7. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Option Overview

    There are different types of treatment for patients with pancreatic NETs. Different types of treatments are available for patients with pancreatic neuroendocrine tumors (NETs). Some treatments are standard (the currently used treatment), and some are being tested in clinical trials. A treatment clinical trial is a research study meant to help improve current treatments or obtain information on new treatments for patients with cancer. When clinical trials show that a new treatment is better than the standard treatment, the new treatment may become the standard treatment. Patients may want to think about taking part in a clinical trial. Some clinical trials are open only to patients who have not started treatment.Six types of standard treatment are used:Surgery An operation may be done to remove the tumor. One of the following types of surgery may be used:Enucleation: Surgery to remove the tumor only. This may be done when cancer occurs in one place in the

  8. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Health Professional Information [NCI] - nci_ncicdr0000062794-nci-header

    This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER.Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment

  9. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Patient Information [NCI] - Stages of Pancreatic Neuroendocrine Tumors

    The plan for cancer treatment depends on where the NET is found in the pancreas and whether it has spread. The process used to find out if cancer has spread within the pancreas or to other parts of the body is called staging. The results of the tests and procedures used to diagnose pancreatic neuroendocrine tumors (NETs) are also used to find out whether the cancer has spread. See the General Information section for a description of these tests and procedures. Although there is a standard staging system for pancreatic NETs, it is not used to plan treatment. Treatment of pancreatic NETs is based on the following: Whether the cancer is found in one place in the pancreas.Whether the cancer is found in several places in the pancreas.Whether the cancer has spread to lymph nodes near the pancreas or to other parts of the body such as the liver, lung, peritoneum, or bone.There are three ways that cancer spreads in the body.The three ways that cancer spreads in the body are:Through tissue.

  10. Pancreatic Cancer Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Stage IV Pancreatic Cancer Treatment

    Treatment Options for Stage IV Pancreatic CancerTreatment options for stage IV pancreatic cancer include the following:Palliative therapy.Chemotherapy: gemcitabine; gemcitabine and erlotinib; or oxaliplatin, irinotecan, leucovorin, and fluorouracil (5-FU) (FOLFIRINOX).[1,2,3,4,5,6,7,8,9,10]Palliative therapyPalliative therapy for advanced pancreatic cancer includes the following:Pain-relieving procedures (e.g., celiac or intrapleural block) and supportive care.[11]Palliative surgical biliary bypass, percutaneous radiologic biliary stent placement, or endoscopically placed biliary stents.[12,13,14]ChemotherapyThe low objective response rate and lack of survival benefit with current chemotherapy indicates that clinical trials are appropriate treatment of all newly diagnosed patients. Occasionally, patients have palliation of symptoms when treated with chemotherapy with well-tested older drugs, such as 5-FU. Gemcitabine has demonstrated activity in patients with pancreatic

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