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Pancreatic Cancer Health Center

Medical Reference Related to Pancreatic Cancer

  1. Stage III Pancreatic Cancer

    Note: Some citations in the text of this section are followed by a level of evidence. The PDQ editorial boards use a formal ranking system to help the reader judge the strength of evidence linked to the reported results of a therapeutic strategy. (Refer to the PDQ summary on Levels of Evidence for more information.) Many patients with stage III pancreatic cancer have tumors that are technically

  2. Cellular Classification of Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

    Table 1. Endocrine Tumors of the PancreasIslet CellsSecreted Active AgentTumor and SyndromeACTH = adrenocorticotropin; MSH = melanocyte-stimulating hormone; VIP = vasoactive intestinal peptide; WDHA = watery diarrhea, hypokalemia, and achlorhydria; 5-HT = serotonin.AlphaGlucagonGlucagonoma (diabetes, dermatitis)BetaInsulinInsulinoma (hypoglycemia)DeltaSomatostatinSomatostatinoma (mild diabetes); diarrhea/steatorrhea; gallstonesDGastrinGastrinoma (peptic ulcer disease)A -> DVIP and/or other undefined mediatorsWDHA5-HTACTHMSHCarcinoidCushing syndromeHyperpigmentationInteracinar CellsSecreted Active AgentTumor and SyndromeFPancreatic polypeptideMultiple hormonal syndromesEC5-HTCarcinoid

  3. Gastrinoma

    The approach to treatment often depends on the results of preoperative localization studies and findings at exploratory laparotomy. At exploration,85% of these tumors are found in the gastrinoma triangle with 40% on the surface of the pancreas and 40% outside of the pancreas. Only 15% are found within the substance of the pancreas. Percutaneous transhepatic venous sampling may occasionally ...

  4. Recurrent Pancreatic Cancer

    Recurrent pancreatic cancer is cancer that has recurred (come back) after it has been treated. The cancer may come back in the pancreas or in other parts of the body. ...

  5. General Information About Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

    Tumors of the endocrine pancreas are a collection of tumor cell types collectively referred to as pancreatic neuroendocrine tumors (NETs). These tumors originate in islet cells. Although they may be similar or identical in histologic appearance to carcinoid tumors of the gastrointestinal tract, differences in their underlying biology and likely differences in response to therapeutic agents suggest that they should be treated and investigated as a distinct entity.[1] They are uncommon cancers with about 1,000 new cases per year in the United States.[2] They account for 3% to 5% of pancreatic malignancies and overall have a better prognosis than the more common pancreatic exocrine tumors.[2,3] Five-year survival is about 55% when the tumors are localized and resected but only about 15% when the tumors are not resectable.[3] Overall 5-year survival rate is about 42%.[2]Figure 1. Cancer of the Pancreas: Relative Survival Rates (%) by Histologic Subtype, Ages 20+, 12 SEER Areas,

  6. Cellular Classification of Pancreatic Cancer

    Pancreatic cancer includes the following carcinomas: Malignant Duct cell carcinoma (90% of all cases). Acinar cell carcinoma. Papillary mucinous carcinoma. Signet ring carcinoma. Adenosquamous carcinoma. Undifferentiated carcinoma. Mucinous carcinoma. Giant cell carcinoma. Mixed type (ductal-endocrine or acinar-endocrine). Small cell carcinoma. Cystadenocarcinoma (serous and mucinous ...

  7. About PDQ

    PDQ IS A COMPREHENSIVE CANCER DATABASE AVAILABLE ON NCI'S WEB SITE. PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health,the federal government's focal point for biomedical research. .

  8. Get More Information From NCI

    Get more information on pancreatic cancer treatment. How to contact the National Cancer Institute (NCI) via phone (1-800-4-Cancer), online, or mail. Plus, details on how to search the NCI web site, and how to order NCI publications.

  9. About PDQ

    PDQ IS A COMPREHENSIVE CANCER DATABASE AVAILABLE ON NCI'S WEB SITE. PDQ is the National Cancer Institute's (NCI's) comprehensive cancer information database. Most of the information contained in PDQ is available online at NCI's Web site. PDQ is provided as a service of the NCI. The NCI is part of the National Institutes of Health,the federal government's focal point for biomedical research. .

  10. Treatment Options by Stage

    Stage I Pancreatic Cancer Treatment of stage I pancreatic cancer may include the following: Surgery alone. Surgery with chemotherapy and radiation therapy. A clinical trial of surgery followed by radiation therapy with chemotherapy. Chemotherapy is given before,during,and after the radiation therapy. A clinical trial of surgery followed by chemotherapy. This summary section refers to ...

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