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Pancreatic Cancer Health Center

Medical Reference Related to Pancreatic Cancer

  1. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Health Professional Information [NCI] - General Information About Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

    Tumors of the endocrine pancreas are a collection of tumor cell types collectively referred to as pancreatic neuroendocrine tumors (NETs). These tumors originate in islet cells. Although they may be similar or identical in histologic appearance to carcinoid tumors of the gastrointestinal tract, differences in their underlying biology and likely differences in response to therapeutic agents suggest that they should be treated and investigated as a distinct entity.[1] They are uncommon cancers with about 1,000 new cases per year in the United States.[2] They account for 3% to 5% of pancreatic malignancies and overall have a better prognosis than the more common pancreatic exocrine tumors.[2,3] Five-year survival is about 55% when the tumors are localized and resected but only about 15% when the tumors are not resectable.[3] Overall 5-year survival rate is about 42%.[2]Figure 1. Cancer of the Pancreas: Relative Survival Rates (%) by Histologic Subtype, Ages 20+, 12 SEER Areas,

  2. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Health Professional Information [NCI] - Recurrent and Progressive Pancreatic Neuroendocrine Tumors

    There is no established therapy for pancreatic neuroendocrine tumors that recur or progress after prior therapy.[1] Deciding on further treatment depends on many factors, including:The specific cancer.Prior treatment.Site of recurrence.Individual patient considerations.Attempts at re-resection of local tumors that have recurred or metastatic lesions may offer palliation, when technically feasible. Intra-arterial chemotherapy is a consideration for patients with liver metastases. Patients with hepatic-dominant disease and substantial symptoms caused by tumor bulk or hormone-release syndromes may benefit from continuous-infusion intra-arterial chemotherapy or procedures that reduce hepatic arterial blood flow to metastases (hepatic arterial occlusion with embolization or with chemoembolization).[2,3,4,5,6,7] Such treatment may also be combined with systemic chemotherapy. A variety of systemic agents have shown biologic or palliative activity,[1,8] including:Somatostatin

  3. Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Patient Information [NCI] - About This PDQ Summary

    About PDQPhysician Data Query (PDQ) is the National Cancer Institute's (NCI's) comprehensive cancer information database. The PDQ database contains summaries of the latest published information on cancer prevention, detection, genetics, treatment, supportive care, and complementary and alternative medicine. Most summaries come in two versions. The health professional versions have detailed information written in technical language. The patient versions are written in easy-to-understand, nontechnical language. Both versions have cancer information that is accurate and up to date and most versions are also available in Spanish.PDQ is a service of the NCI. The NCI is part of the National Institutes of Health (NIH). NIH is the federal government's center of biomedical research. The PDQ summaries are based on an independent review of the medical literature. They are not policy statements of the NCI or the NIH.Purpose of This SummaryThis PDQ cancer information summary has current

  4. Pancreatic Neuroendocrine Tumors (NETs)

    Pancreatic neuroendocrine tumors may or may not be cancer. Treatment for these rare tumors depends on what kind they are and how far they have spread.

  5. Pancreatic Cancer Treatments by Stage

    WebMD looks into both routinely used and emerging treatments for pancreatic cancer.

  6. Pancreatic Cancer Diet and Prevention

    WebMD looks at ways you can improve your health and decrease your risk of getting pancreatic cancer. Learn about lifestyle changes and more.

  7. Pancreatic Cancer Symptoms

    WebMD examines the signs and symptoms of pancreatic cancer, including abdominal pain, weight loss, jaundice, and more.

  8. Pancreatic Cancer Diagnosis and Early Detection

    WebMD explains how pancreatic cancer is diagnosed and if there is a way to detect it early.

  9. Pancreatic Cancer Causes and Risk Factors

    Are you at risk for pancreatic cancer? Learn more from the experts at WebMD.

  10. Questions to Ask Your Doctor About Pancreatic Cancer

    WebMD provides you with questions to ask your doctor if you've been diagnosed with pancreatic cancer.

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