Early pancreatic cancers usually cause few symptoms, most of which are vague. Because signs and symptoms of most pancreatic cancer may be mistaken for less-serious digestive problems, the disease is rarely detected before it has spread to nearby tissues or distant organs via the bloodstream or lymphatic system. Symptoms that may arise include:
Significant weight loss accompanied by abdominal pain -- the most likely warning signs.
Vague but gradually worsening abdominal pain that may decrease...
Pain relief by celiac axis nerve or intrapleural block (percutaneous).
Other palliative medical care alone.
Treatment options under clinical evaluation:
Clinical trials evaluating pharmacologic modulation of fluorinated pyrimidines, new anticancer agents, or biologicals (phase I and II).
Current Clinical Trials
Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with recurrent pancreatic cancer. The list of clinical trials can be further narrowed by location, drug, intervention, and other criteria.
General information about clinical trials is also available from the NCI Web site.
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