Skip to content
My WebMD Sign In, Sign Up

Pancreatic Cancer Health Center

Font Size

Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®): Treatment - Patient Information [NCI] - Treatment Options for Pancreatic Neuroendocrine Tumors

continued...

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with insulinoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Glucagonoma

Treatment may include the following:

  • For one small tumor in the head or tail of the pancreas, treatment is usually surgery to remove the tumor.
  • For one large tumor in the head of the pancreas that cannot be removed by surgery, treatment is usually pancreatoduodenectomy (surgery to remove the head of the pancreas, the gallbladder, nearby lymph nodes and part of the stomach, small intestine, and bile duct).
  • For more than one tumor in the pancreas, treatment is usually surgery to remove the tumor or surgery to remove the body and tail of the pancreas.
  • For tumors that have spread to lymph nodes or other parts of the body, treatment may include the following:
    • Surgery to remove the tumor.
    • Radiofrequency ablation or cryosurgical ablation, if the tumor cannot be removed by surgery.
  • For tumors that cannot be removed by surgery, treatment may include the following:
    • Combination chemotherapy.
    • Hormone therapy.
    • Radiofrequency ablation or cryosurgical ablation.
  • If the cancer mostly affects the liver and the patient has severe symptoms from hormones or from the size of tumor, treatment may include:
    • Hepatic arterial occlusion, with or without systemic chemotherapy.
    • Chemoembolization, with or without systemic chemotherapy.

Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with glucagonoma. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

Other Pancreatic Neuroendocrine Tumors (Islet Cell Tumors)

For VIPoma, treatment may include the following:

  • Fluids and hormone therapy to replace fluids and electrolytes that have been lost from the body.
  • Surgery to remove the tumor and nearby lymph nodes.
  • Surgery to remove as much of the tumor as possible when the tumor cannot be completely removed or has spread to distant parts of the body. This is palliative therapy to relieve symptoms and improve the quality of life.
  • For tumors that have spread to lymph nodes or other parts of the body, treatment may include the following:
    • Surgery to remove the tumor.
    • Radiofrequency ablation or cryosurgical ablation, if the tumor cannot be removed by surgery.
  • For tumors that continue to grow during treatment or have spread to other parts of the body, treatment may include the following:
    • Chemotherapy.
    • Targeted therapy.
1|2|3

WebMD Public Information from the National Cancer Institute

Last Updated: February 25, 2014
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Next Article:

Today on WebMD

Pancreatic Cancer Symptoms And Treatment
SLIDESHOW
what is your cancer risk
HEALTH CHECK
 
cancer fighting foods
SLIDESHOW
Pancreatic Cancer Diagnosis And Early Detection
REFERENCE
 
Integrative Medicine Cancer Quiz
QUIZ
Patrick Swayzes Widow Healing From Loss
FEATURE
 
Pets Improve Your Health
SLIDESHOW
Resolved To Quit Smoking
SLIDESHOW
 

WebMD Special Sections