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    Radiation Therapy for Nonmelanoma Skin Cancer

    Radiation therapy is used to destroy cancer cells. This procedure may require 15 to 30 visits to a facility with special equipment. Radiation therapy may be used in combination with other types of therapy to treat aggressive or recurrent skin cancer.

    What To Expect After Treatment

    Recovery time may vary depending on the site treated and the amount of radiation used.

    Why It Is Done

    Radiation therapy may be used:

    • If you are older than 60.
    • For skin cancers that are too large or deep to be treated with surgery or with surgery alone.
    • For skin cancers in places that are hard to treat with surgery, such as the eyelid, ear, or nose.
    • For skin cancers that have come back after surgery (recurrent).
    • To relieve symptoms but not to cure the skin cancer (palliative treatment).

    How Well It Works

    Surgery and radiation are the primary treatments for nonmelanoma skin cancer, but studies show that surgery has the best results.1 Still, radiation therapy has very good cure rates and cosmetic results, so sometimes it is the treatment of choice.


    Risks of radiation therapy to treat skin cancer include the following:

    • New skin cancers may occur in the surrounding area.
    • Skin cancers may come back after radiation therapy and be harder to treat successfully.
    • Skin may become dry and hairless. Or skin may lose color or become easily infected (chronic radiation dermatitis).
    • Skin may shrink and waste away (skin atrophy).
    • Healthy skin may be destroyed by radiation (cutaneous necrosis).

    Side effects are common but typically go away when treatment is finished. They include:

    What To Think About

    Radiation therapy is most often reserved for use in older adults. It may lead to other skin cancers in younger people as they age.

    Complete the special treatment information form (PDF)(What is a PDF document?) to help you understand this treatment.


    1. National Comprehensive Cancer Network (2012). Basal cell and squamous cell skin cancers. NCCN Clinical Practice Guidelines in Oncology, Version 2. Available online:

    ByHealthwise Staff
    Primary Medical ReviewerE. Gregory Thompson, MD - Internal Medicine
    Specialist Medical ReviewerAmy McMichael, MD - Dermatology

    Current as ofNovember 14, 2014

    WebMD Medical Reference from Healthwise

    Last Updated: November 14, 2014
    This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.

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