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Treatment Options by Stage

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    Patients who have had treatment that saves the sphincter muscles may receive follow-up exams every 3 months for the first 2 years, including rectal exams with endoscopy and biopsy, as needed.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage II anal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Stage IIIA Anal Cancer

    Treatment of stage IIIA anal cancer may include the following:

    • External-beam radiation therapy with chemotherapy. If cancer remains after treatment, more chemotherapy and radiation therapy may be given to avoid the need for a permanent colostomy.
    • Internal radiation therapy.
    • Abdominoperineal resection, if cancer remains or comes back after treatment with chemotherapy and radiation therapy.
    • A clinical trial of new treatment options.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IIIA anal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Stage IIIB Anal Cancer

    Treatment of stage IIIB anal cancer may include the following:

    • External-beam radiation therapy with chemotherapy.
    • Local resection or abdominoperineal resection, if cancer remains or comes back after treatment with chemotherapy and radiation therapy. Lymph nodes may also be removed.
    • A clinical trial of new treatment options.

    Check for U.S. clinical trials from NCI's list of cancer clinical trials that are now accepting patients with stage IIIB anal cancer. For more specific results, refine the search by using other search features, such as the location of the trial, the type of treatment, or the name of the drug. General information about clinical trials is available from the NCI Web site.

    Stage IV Anal Cancer

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